Rabbit Polyclonal PDK1 antibody. Suitable for WB and reacts with Human, Pig, Mouse, Rat, Rabbit, African green monkey, Dog samples. Cited in 8 publications. Immunogen corresponding to Synthetic Peptide within Human PDK1 conjugated to Keyhole Limpet Haemocyanin.
Images
Publications
Filter by
- Advances in clinical and experimental medicine : official organ Wroclaw Medical University 29:785-7922020PD-L1, PDK-1 and p-Akt are correlated in patients with papillary thyroid carcinoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHui Wang,Zhengdong Zhang,Zhe Yan,Shihong MaPubMed 32750756
- American journal of physiology. Regulatory, integr 317:R513-R5202019Increased pyruvate dehydrogenase activity in skeletal muscle of growth-restricted ovine fetuses.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlexander L Pendleton et. al.PubMed 31314546
- The Journal of biological chemistry 294:7810-78202019Lactic acidosis caused by repressed lactate dehydrogenase subunit B expression down-regulates mitochondrial oxidative phosphorylation via the pyruvate dehydrogenase (PDH)-PDH kinase axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSun Mi Hong et. al.PubMed 30923124
- Pflugers Archiv : European journal of physiology 470:1597-16132018Impact of skeletal muscle IL-6 on regulation of liver and adipose tissue metabolism during fasting.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLærke Bertholdt et. al.PubMed 30069669
- Pflugers Archiv : European journal of physiology 470:1633-16452018Training state and fasting-induced PDH regulation in human skeletal muscle.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnders Gudiksen et. al.PubMed 29946822
- Neuro-oncology 20:343-3542017Metabolic heterogeneity and plasticity of glioma stem cells in a mouse glioblastoma model.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShunsuke Shibao,Noriaki Minami,Naoyoshi Koike,Nobuyuki Fukui,Kazunari Yoshida,Hideyuki Saya,Oltea SampetreanPubMed 29016888
- American journal of physiology. Endocrinology and metabolism 312:E204-E2142016Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnders Gudiksen,Laerke Bertholdt,Mikkel Birkkjaer Vingborg,Henriette Watson Hansen,Stine Ringholm,Henriette PilegaardPubMed 28028037
- PloS one 11:e01564602016Lack of Skeletal Muscle IL-6 Affects Pyruvate Dehydrogenase Activity at Rest and during Prolonged Exercise.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human PDK1 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link Q15118
Consider this alternative
Reactivity data
Select an application| WB | |
|---|---|
| Human | Tested |
| Mouse | Tested |
| Rat | Tested |
| African green monkey | Tested |
| Dog | Expected |
| Pig | Tested |
| Rabbit | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 | Notes - |
Species Pig | Dilution info 1/1000 | Notes - |
Species Mouse | Dilution info 1/1000 | Notes - |
Species Rat | Dilution info 1/1000 | Notes - |
Species Rabbit | Dilution info 1/1000 | Notes - |
Species African green monkey | Dilution info 1/1000 | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Dog | Dilution info 1/1000 | Notes - |
Associated Products
Select an associated product type
6 products for Alternative Product
Target data
Function
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
Alternative names
PDHK1, PDK1, Pyruvate dehydrogenase kinase isoform 1, PDH kinase 1
Recommended products
Rabbit Polyclonal PDK1 antibody. Suitable for WB and reacts with Human, Pig, Mouse, Rat, Rabbit, African green monkey, Dog samples. Cited in 8 publications. Immunogen corresponding to Synthetic Peptide within Human PDK1 conjugated to Keyhole Limpet Haemocyanin.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
Preservative: 0.09% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human PDK1 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information. Database link Q15118
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-PDK1 antibody (ab90444)
All lanes: Western blot - Anti-PDK1 antibody (ab90444) at 1/1000 dilution
Lane 1: HeLa cell lysate
Lane 2: Rat brain lysate
Lane 3: Mouse brain lysate
Lane 4: Vero cell lysate
Lane 5: ESK-4 cell lysate
Lane 6: RK-13 cell lysate
Lane 7: MDCK cell lysate
Predicted band size: 49 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com