JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB187971

Anti-PDXDC1 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal PDXDC1 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human PDXDC1 aa 1-100.

View Alternative Names

KIAA0251, PDXDC1, Pyridoxal-dependent decarboxylase domain-containing protein 1

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDXDC1 antibody (AB187971)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDXDC1 antibody (AB187971)

Immunohistochemical analysis of paraffin-embedded Human colon tissue labeling PDXDC1 with ab187971 at 1/200 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-PDXDC1 antibody (AB187971)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-PDXDC1 antibody (AB187971)

Immunofluorescence analysis of Human cell line U-2 OS labeling PDXDC1 with ab187971 at 4 μg/ml.

Western blot - Anti-PDXDC1 antibody (AB187971)
  • WB

Supplier Data

Western blot - Anti-PDXDC1 antibody (AB187971)

All lanes:

Western blot - Anti-PDXDC1 antibody (ab187971) at 1/100 dilution

All lanes:

RT-4 cell lysates

Predicted band size: 87 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human PDXDC1 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q6P996

style
left-column

Complementary Products

Primary Antibodies

AB126482

Anti-ZCWPW2 antibody

Immunocytochemistry/ Immunofluorescence - Anti-ZCWPW2 antibody (AB126482)

  • 0
  • 0
Primary Antibodies

AB184772

Anti-URG11 antibody

Immunocytochemistry/ Immunofluorescence - Anti-URG11 antibody (AB184772)

  • 4
  • 2
Primary Antibodies

AB188127

Anti-YIF1B antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-YIF1B antibody (AB188127)

  • 0
  • 0
Primary Antibodies

AB223477

Anti-ZKSCAN3 antibody

Immunocytochemistry/ Immunofluorescence - Anti-ZKSCAN3 antibody (AB223477)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

PDXDC1 also known as pyridoxal-dependent decarboxylase domain containing 1 functions as an enzyme involved in amino acid metabolism. This protein has a molecular mass of approximately 57 kDa. It is expressed in various tissues including liver kidney and muscle. PDXDC1 contains domains that suggest it may play a role in pyridoxal phosphate-dependent enzymatic reactions which are essential for certain metabolic processes.
Biological function summary

The activity of pyridoxal phosphate enzymes influences the synthesis and degradation of amino acids. PDXDC1 may form part of a larger enzymatic complex that facilitates these pathways ensuring cellular processes maintain proper amino acid levels. By participating in these reactions PDXDC1 helps cellular metabolism leading to the production of important metabolic intermediates required for energy balance and synthesis of biomolecules.

Pathways

Amino acid metabolism and its interconnections are influenced by PDXDC1. This protein interacts with pivotal pathways like the urea cycle and gluconeogenesis affecting energy production and nitrogen disposal. PDXDC1 has possible interactions with related proteins such as alanine aminotransferase which collaborates in the transamination and disposal of nitrogen.

Aberrant expression or mutation of PDXDC1 may connect to metabolic disorders and liver diseases. Metabolic imbalance involving amino acid metabolism potentially links PDXDC1 to liver dysfunction and metabolic syndrome. In disease conditions PDXDC1 may associate with proteins like glutamate dehydrogenase which plays a role in amino acid catabolism influencing the progression or management of related disorders.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information PDXDC1
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 11:988 PubMed32080171

2020

A serine/threonine protein kinase encoding gene KERNEL NUMBER PER ROW6 regulates maize grain yield.

Applications

Unspecified application

Species

Unspecified reactive species

Haitao Jia,Manfei Li,Weiya Li,Lei Liu,Yinan Jian,Zhixing Yang,Xiaomeng Shen,Qiang Ning,Yanfang Du,Ran Zhao,David Jackson,Xiaohong Yang,Zuxin Zhang
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com