PE Anti-alpha smooth muscle Actin antibody [SP171]
- RabMAb
- Recombinant
- What is this?
Be the first to review this product! Submit a review
|
(0 Publication)
Rabbit Recombinant Monoclonal alpha smooth muscle Actin antibody - conjugated to PE.
View Alternative Names
ACTSA, ACTVS, GIG46, ACTA2, Alpha-actin-2, Cell growth-inhibiting gene 46 protein
Related conjugates and formulations (9)
-
665 Alexa Fluor® 647
Alexa Fluor® 647 Anti-alpha smooth muscle Actin antibody [SP171]
-
519 Alexa Fluor® 488
Alexa Fluor® 488 Anti-alpha smooth muscle Actin antibody [SP171]
-
660 APC
APC Anti-alpha smooth muscle Actin antibody [SP171]
-
617 Alexa Fluor® 594
Alexa Fluor® 594 Anti-alpha smooth muscle Actin antibody [SP171]
-
603 Alexa Fluor® 568
Alexa Fluor® 568 Anti-alpha smooth muscle Actin antibody [SP171]
-
565 Alexa Fluor® 555
Alexa Fluor® 555 Anti-alpha smooth muscle Actin antibody [SP171]
-
775 Alexa Fluor® 750
Alexa Fluor® 750 Anti-alpha smooth muscle Actin antibody [SP171]
-
Anti-alpha smooth muscle Actin antibody [SP171]
-
Anti-alpha smooth muscle Actin antibody [SP171] - BSA and Azide free
Product details
What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Alpha smooth muscle actin aids in maintaining the structural integrity of tissues by forming part of the actin cytoskeleton an important element in cellular support. It exists in high concentration in stress fibers contributing to cellular movements and shape maintenance. These actions are essential in various dynamic cellular processes such as cell migration and adhesion. Alpha smooth muscle actin does not typically form complexes but it associates with other components of the actin cytoskeleton to ensure cell stability and function.
Pathways
Alpha smooth muscle actin functions significantly within the TGF-beta signaling pathway which influences cell proliferation differentiation and apoptosis. It interacts closely with proteins such as myosin to facilitate cellular contractility and motility. Additionally α-SMA plays a part in the RhoA/Rho kinase (ROCK) pathway connecting with regulators of actin filament organization. These pathways are essential for modulation of smooth muscle contraction and actin filament assembly contributing to vascular development and wound healing.
Product protocols
- Visit the General protocols
- Visit the Troubleshooting
Target data
Complementary Products
Product promise
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com