JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB215753

PE Anti-CD31 antibody [C31.7]

Be the first to review this product! Submit a review

|

(5 Publications)

Mouse Monoclonal CD31 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PECAM1.

View Alternative Names

CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1

1 Images
Flow Cytometry - PE Anti-CD31 antibody [C31.7] (AB215753)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-CD31 antibody [C31.7] (AB215753)

Flow cytometry analysis of Jurkat cells labeling CD31 using ab215753 at 5 μL per 106 cells (red).

Controls : Cells alone (black) and isotype control (green).

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

C31.7

Isotype

IgG1

Light chain type

kappa

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Full Length Protein corresponding to Human PECAM1.

P16284

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>5 μL per test per one million cells in 0.1 mL or 5 μL per 100 μL of whole blood.</p>" }, "Monkey": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" }, "Rabbit": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed : 17580308, PubMed : 19342684). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed : 19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed : 27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed : 17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed : 12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed : 12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed : 18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed : 18672896). Induces susceptibility to atherosclerosis (By similarity).. Isoform Delta15. Does not protect against apoptosis.
See full target information PECAM1

Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Nursing & health sciences 24:312-321 PubMed35157362

2022

Angiopoietin-like protein 4 treated bone marrow-derived mesenchymal stem cells alleviate myocardial injury of patients with myocardial infarction.

Applications

Unspecified application

Species

Unspecified reactive species

Fen Zhang,Jie Wu,Xingxing Li,Xuan Ying,Wenbing Fang,Yang Dong

Cellular and molecular neurobiology : PubMed33108594

2020

A Progressive Loss of phosphoSer138-Profilin Aligns with Symptomatic Course in the R6/2 Mouse Model of Huntington's Disease: Possible Sex-Dependent Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Akanksha Baharani,Zelan Wei,William J Roesler,Darrell D Mousseau

Inhalation toxicology 32:131-140 PubMed32312128

2020

Impairment of endothelial progenitor cells function in patient with mustard gas intoxication.

Applications

Unspecified application

Species

Unspecified reactive species

Vahid Siavashi,Hadi Cheraghi,Pirouz Pourmohammad,Parviz Nooshirvani,Sara Abdolahi,Amir Solghani,Seyed Mahdi Nassiri,Tooba Ghazanfari

Biomaterials 241:119904 PubMed32109705

2020

Mussel-inspired "built-up" surface chemistry for combining nitric oxide catalytic and vascular cell selective properties.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangyang Li,Jingxia Liu,Tong Yang,Hua Qiu,Lei Lu,Qiufen Tu,Kaiqing Xiong,Nan Huang,Zhilu Yang

Biomaterials 207:10-22 PubMed30947118

2019

Biomimetic engineering endothelium-like coating on cardiovascular stent through heparin and nitric oxide-generating compound synergistic modification strategy.

Applications

Unspecified application

Species

Unspecified reactive species

Hua Qiu,Pengkai Qi,Jingxia Liu,Ying Yang,Xing Tan,Yu Xiao,Manfred F Maitz,Nan Huang,Zhilu Yang
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com