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AB178451

PE Anti-CD35 antibody [E11]

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(2 Publications)

Mouse Monoclonal CD35 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing CR1 protein.

View Alternative Names

CD35, C3BR, CR1, Complement receptor type 1, C3b/C4b receptor

2 Images
Flow Cytometry - PE Anti-CD35 antibody [E11] (AB178451)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-CD35 antibody [E11] (AB178451)

Flow cytometric analysis of Human peripheral whole blood cells labelling CD35 with ab178451 at 0.56 μg/ml.

Flow Cytometry - PE Anti-CD35 antibody [E11] (AB178451)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-CD35 antibody [E11] (AB178451)

Flow cytometric analysis of Human peripheral whole blood cells labelling CD35 with ab178451 at 0.56 μg/ml.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

E11

Isotype

IgG1

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing CR1 protein. The exact immunogen used to generate this antibody is proprietary information.

P17927

Specificity

This antibody recognizes CD35, a type I glycoprotein expressed on granulocytes, monocytes, B cells, folicular dendritic cells, erythrocytes, NK and T cell subsets, as well as e.g. on glomerulal podocytes.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>10 μl reagent / 100 μl of whole blood or 10<sup>6</sup> cells in a suspension.</p>" }, "Primates": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Purification notes
The purified antibody is conjugated with R-Phycoerythrin (PE) under optimumconditions. The conjugate is purified by size-exclusion chromatography andadjusted for direct use.
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 0.2% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages (PubMed : 2963069). Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation (PubMed : 2963069). Also acts in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d (PubMed : 2972794, PubMed : 8175757). Also plays a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells (PubMed : 25742728).. (Microbial infection) Acts as a receptor for Epstein-Barr virus.
See full target information CR1
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

iScience 27:109048 PubMed38464592

2024

Specific knockout of macrophage SHP2 promotes macrophage M2 polarization and alleviates renal ischemia-reperfusion injury.

Applications

Unspecified application

Species

Unspecified reactive species

Meilian Du,Shanbao Zhang,Xiaoyu Wang,Chen Liu,Linrong Pan,Xiao Chen,Yinghui Qi

Cytometry. Part A : the journal of the International Society for Analytical Cytology 81:165-8 PubMed22170815

2011

Identification of a cross-reacting, monoclonal anti-human CD233 antibody for identification and sorting of rhesus macaque erythrocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Colleen Byrnes,Y Terry Lee,Robert E Donahue,Jeffery L Miller
View all publications
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Product promise

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