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AB18282

PE Anti-CD4 antibody [MEM-241]

2

(6 Reviews)

|

(6 Publications)

Mouse Monoclonal CD4 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CD4.

View Alternative Names

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

1 Images
Flow Cytometry - PE Anti-CD4 antibody [MEM-241] (AB18282)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-CD4 antibody [MEM-241] (AB18282)

ab18282 staining CD4 in human T cells by Flow Cytometry .

  • 660 APC

    APC Anti-CD4 antibody [MEM-241]

  • 785 APC/Cy7®

    APC/Cy7® Anti-CD4 antibody [MEM-241]

  • 723 Alexa Fluor® 700

    Alexa Fluor® 700 Anti-CD4 antibody [MEM-241]

  • Biotin

    Biotin Anti-CD4 antibody [MEM-241]

  • 519 FITC

    FITC Anti-CD4 antibody [MEM-241]

  • 778 PE/Cy7®

    PE/Cy7® Anti-CD4 antibody [MEM-241]

  • 675 PerCP

    PerCP Anti-CD4 antibody [MEM-241]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-241

Isotype

IgG1

Light chain type

kappa

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Fragment Protein within Human CD4. The exact immunogen used to generate this antibody is proprietary information.

P01730

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Complementary Products

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use 5-20μl for 100μl whole human blood cells.</p><p><a href='/en-us/products/primary-antibodies/pe-mouse-igg1-b11-6-isotype-control-ab91357'>ab91357</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }
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Product details

The purified antibody is conjugated with R-Phycoerythrin (R-PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: BSA, PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4
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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Applied biochemistry and biotechnology 196:6189-6199 PubMed38224392

2024

Th9 Cytokines Inhibit Proliferation, Promote Apoptosis, and Immune Escape in Thyroid Carcinoma Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xinyu Ying,Xinyi Ma,Ziru Yang,Bo Zhou

Cell death & disease 13:160 PubMed35181676

2022

HOXA-AS2 contributes to regulatory T cell proliferation and immune tolerance in glioma through the miR-302a/KDM2A/JAG1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Chuanhong Zhong,Bei Tao,Xianglong Li,Wei Xiang,Lilei Peng,Tangming Peng,Ligang Chen,Xiangguo Xia,Jian You,Xiaobo Yang

Micromachines 11: PubMed32630535

2020

Improved Enumeration of Weakly Fluorescent CD4+ T-lymphocytes by Confining Cells in a Spinning Sample Cartridge with a Helical Minichannel.

Applications

Unspecified application

Species

Unspecified reactive species

Subin Kim,Jakir Hossain Imran,Mohiuddin Khan Shourav,Jung Kyung Kim

Lab on a chip 19:589-597 PubMed30648711

2019

Two-level submicron high porosity membranes (2LHPM) for the capture and release of white blood cells (WBCs).

Applications

Unspecified application

Species

Unspecified reactive species

Javier Alejandro Hernández-Castro,Kebin Li,Jamal Daoud,David Juncker,Teodor Veres

Traffic (Copenhagen, Denmark) 16:1330-41 PubMed26771955

2015

Munc18-2 is required for Syntaxin 11 Localization on the Plasma Membrane in Cytotoxic T-Lymphocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Nele M G Dieckmann,Yvonne Hackmann,Maurizio Aricò,Gillian M Griffiths

Cell journal 13:281-9 PubMed23507624

2012

The Effects of Isoproterenol and Propranolol on Cytokine Profile Secretion by Cultured Tumor-infiltrating Lymphocytes Derived from Colorectal Cancer Patients.

Applications

Unspecified application

Species

Unspecified reactive species

Shahram Seyedi,Alireza Andalib,Abbas Rezaei,Seyed Mohsen Hosseini,Seyed Reza Mohebbi,Mohammad Reza Zali,Mohamad Vafai,Roubik Behboo,Seyed Abbas Tabatabaei,Shahram Shahabi
View all publications
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Product promise

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