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AB134381

PE Anti-CD40 antibody [5C3]

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(1 Publication)

Mouse Monoclonal CD40 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human CD40.

View Alternative Names

CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40

1 Images
Flow Cytometry - PE Anti-CD40 antibody [5C3] (AB134381)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-CD40 antibody [5C3] (AB134381)

Flow cytometry analysis of normal Human peripheral blood cells with Mouse IgG1 K Isotype Control PE (blue histogram) or ab134381 at 5 µl (0.015 µg)/ test (purple histogram). Cells in the lymphocyte gate were used for analysis.

  • Unconjugated

    Anti-CD40 antibody [5C3] - Low endotoxin, Azide free

  • 519 FITC

    FITC Anti-CD40 antibody [5C3]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

5C3

Isotype

IgG1

Light chain type

kappa

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Full Length Protein corresponding to Human CD40.

P25942

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "5 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

Product details

The 5C3 clone is reported to be used for activation of B cells in in vitro functional assays.

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.2% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Receptor for TNFSF5/CD40LG (PubMed : 31331973). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).
See full target information CD40

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

JCI insight 9: PubMed38227377

2024

C3aR-initiated signaling is a critical mechanism of podocyte injury in membranous nephropathy.

Applications

Unspecified application

Species

Unspecified reactive species

Qi Zhang,Sofia Bin,Kelly Budge,Astgik Petrosyan,Valentina Villani,Paola Aguiari,Coralien Vink,Jack Wetzels,Hasmik Soloyan,Gaetano La Manna,Manuel Alfredo Podestà,Paolo Molinari,Sargis Sedrakyan,Kevin V Lemley,Roger E De Filippo,Laura Perin,Paolo Cravedi,Stefano Da Sacco
View all publications

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