AB134372

PE Anti-CD41 antibody [MEM-06]

Name: PE Anti-CD41 antibody [MEM-06] (ab134372) | Abcam
Brand: Abcam Limited
SKU: AB134372
Price: 110 USD
Availability: InStock

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(2 Publications)

Mouse Monoclonal CD41 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing ITGA2B protein.

View Alternative Names

CD41, GP2B, ITGAB, ITGA2B, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb

2 Images

Flow Cytometry - PE Anti-CD41 antibody [MEM-06] (AB134372)

Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-CD41 antibody [MEM-06] (AB134372)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab134372 (20 μl reagent / 100 μl of peripheral whole blood).

Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-CD41 antibody [MEM-06] (AB134372)

Separation of human CD41 positive CD45 negative thrombocytes (red-filled) from CD41 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using ab134372 (20 μl reagent / 100 μl of peripheral whole blood).

Unconjugated

Anti-CD41 antibody [MEM-06]
667 PE/Cy5®

PE/Cy5® Anti-CD41 antibody [MEM-06]
519 FITC

FITC Anti-CD41 antibody [MEM-06]
Biotin

Biotin Anti-CD41 antibody [MEM-06]
660 APC

APC Anti-CD41 antibody [MEM-06]
778 PE/Cy7®

PE/Cy7® Anti-CD41 antibody [MEM-06]
723 Alexa Fluor® 700

Alexa Fluor® 700 Anti-CD41 antibody [MEM-06]
675 PerCP

PerCP Anti-CD41 antibody [MEM-06]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-06

Isotype

IgG1

Conjugation

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing ITGA2B protein. The exact immunogen used to generate this antibody is proprietary information.

P08514

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "20 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>Use 20 μl reagent / 100 μl of whole blood or 10^6 cells in a suspension.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Size-exclusion chromatography

Purification notes

ab134372 is conjugated with R-Phycoerythrin (PE) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use.

Storage buffer

pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS, 0.2% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Integrin alpha-IIb/beta-3 (ITGA2B : ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed : 9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity). Integrin ITGA2B : ITGB3 is also the receptor of erythrocyte-specific ICAM4 ligand involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets (PubMed : 12477717).

See full target information ITGA2B

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Nanoscale advances 5:4435-4446 PubMed37638157

2023

Separation and isolation of CD9-positive extracellular vesicles from plasma using flow cytometry.

Applications

Unspecified application

Species

Unspecified reactive species

Karan Khanna,Nikki Salmond,Sina Halvaei,Andrew Johnson,Karla C Williams

Proceedings of the National Academy of Sciences of the United States of America 120:e2207993120 PubMed37428931

2023

NOS inhibition reverses TLR2-induced chondrocyte dysfunction and attenuates age-related osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Ping Shen,Sebastian Serve,Peihua Wu,Xiaohui Liu,Yujie Dai,Nayar Durán-Hernández,Dan Thi Mai Nguyen,Michael Fuchs,Tazio Maleitzke,Marie-Jacqueline Reisener,Maria Dzamukova,Katrin Nussbaumer,Tobias M Brunner,Yonghai Li,Vivien Holecska,Gitta A Heinz,Frederik Heinrich,Pawel Durek,Georgia Katsoula,Clemens Gwinner,Tobias Jung,Eleftheria Zeggini,Tobias Winkler,Mir-Farzin Mashreghi,Matthias Pumberger,Carsten Perka,Max Löhning

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

PE Anti-CD41 antibody [MEM-06]

Flow Cytometry - PE Anti-CD41 antibody [MEM-06] (AB134372)

Flow Cytometry - PE Anti-CD41 antibody [MEM-06] (AB134372)

Related conjugates and formulations (8)

Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Product protocols

Target data

Publications (2)

Product promise