Mouse Monoclonal CD44 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing CD44 protein.
Images
![Flow Cytometry - PE Anti-CD44 antibody [MEM-85] (AB269300), expandable thumbnail](https://content.abcam.com/products/images/pe-cd44-antibody-mem-85-ab269300--flow-cytometry-img13621.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - PE Anti-CD44 antibody [MEM-85] (AB269300)")
Publications
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- Journal of translational medicine 21:7212023Cancer stem cell-derived CHI3L1 activates the MAF/CTLA4 signaling pathway to promote immune escape in triple-negative breast cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShufeng Ji,Hao Yu,Dan Zhou,Xulong Fan,Yan Duan,Yijiang Tan,Min Lang,Guoli ShaoPubMed 37838657
- Animals : an open access journal from MDPI 13:2022Isolation and Identification of Bone Marrow Mesenchymal Stem Cells from Forest Musk Deer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWeiqiang Luo,Yangyang Geng,Mengxi Gao,Mengting Cao,Junjian Wang,Jing Yang,Chenxuan Sun,Xingrong YanPubMed 36611625
- Bioengineered 13:3896-39102022Ultrasound targeted microbubble destruction-mediated SOCS3 attenuates biological characteristics and epithelial-mesenchymal transition (EMT) of breast cancer stem cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXiaojiang Tang,Na Hao,Yuhui Zhou,Yang LiuPubMed 35109743
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Conjugation
- PE
- Excitation/Emission
- Ex: 480;565nm, Em: 578nm
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Cell preparation containing CD44 protein. The exact immunogen used to generate this antibody is proprietary information. Database link P16070
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Human | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 10 µL for 106 Cells | Notes - |
Associated Products
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Target data
Function
Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment (PubMed:16541107, PubMed:19703720, PubMed:22726066). Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection (PubMed:7528188). Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:18757307, PubMed:23589287). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (PubMed:15123640).
Alternative names
CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I
Recommended products
Mouse Monoclonal CD44 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing CD44 protein.
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Conjugation
- PE
- Excitation/Emission
- Ex: 480;565nm, Em: 578nm
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Cell preparation containing CD44 protein. The exact immunogen used to generate this antibody is proprietary information. Database link P16070
- Clone number
- MEM-85
- Purification technique
- Size-exclusion chromatography
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Store in the dark
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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1 product image
![Flow Cytometry - PE Anti-CD44 antibody [MEM-85] (ab269300), expandable thumbnail](https://content.abcam.com/products/images/pe-cd44-antibody-mem-85-ab269300--flow-cytometry-img13621.jpg "Flow Cytometry - PE Anti-CD44 antibody [MEM-85] (ab269300)")
Flow Cytometry - PE Anti-CD44 antibody [MEM-85] (ab269300)
Flow cytometry analysis (surface staining) of human peripheral blood cells labeling CD44 with ab269300.
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