AB269300

PE Anti-CD44 antibody [MEM-85]

Name: Anti-CD44 PE antibody [MEM-85] (ab269300) Mouse monoclonal IgG2b | Abcam
Brand: Abcam Limited
SKU: AB269300
Price: 300 USD
Availability: InStock

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(7 Publications)

Mouse Monoclonal CD44 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 7 publications. Immunogen corresponding to Cell preparation containing CD44 protein.

View Alternative Names

CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I

1 Images

Flow Cytometry - PE Anti-CD44 antibody [MEM-85] (AB269300)

Flow Cyt

Unknown

Flow Cytometry - PE Anti-CD44 antibody [MEM-85] (AB269300)

Flow cytometry analysis (surface staining) of human peripheral blood cells labeling CD44 with ab269300.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-85

Isotype

IgG2b

Conjugation

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing CD44 protein. The exact immunogen used to generate this antibody is proprietary information.

P16070

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Size-exclusion chromatography

Storage buffer

pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Store in the dark

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

The protein expressed by gene CD44 functions as a cell-surface receptor involved in cell-cell interactions, cell adhesion, and migration, allowing cells to detect and react to changes in their tissue microenvironment. It is implicated in numerous cellular processes, including the activation, recirculation, and homing of T-lymphocytes, hematopoiesis, inflammation, and the response to bacterial infection. Through its ectodomain, CD44 interacts with extracellular matrix components like hyaluronan, collagen, growth factors, cytokines, and proteases, serving as a platform for signal transduction by forming protein complexes with receptor kinases and membrane proteases via its cytoplasmic domain. Effectors such as PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases, and phospholipase C coordinate signaling pathways that promote calcium mobilization and actin-mediated cytoskeleton reorganization crucial for cell migration and adhesion. This supplementary information is collated from multiple sources and compiled automatically.

See full target information CD44

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Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Journal of applied oral science : revista FOB 32:e20230444 PubMed40525809

2025

LncRNA XIST facilitates the odontogenic differentiation of dental pulp stem cells via the FUS/ZBTB16.

Applications

Unspecified application

Species

Unspecified reactive species

Ruiqing Cheng,Honglei Sun,Xiaotong Qiao,Xuefang Chen

The Tohoku journal of experimental medicine 263:199-210 PubMed38797699

2024

Arsenic Trioxide Induces Retinoic Acid-Related Orphan Receptor Beta and Blocks the WNT Pathway to Inhibit Stemness in Glioblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Dacheng Ding,Kaiming Gao,Xuebin Zhang,Hu Wang

iScience 27:108957 PubMed38333692

2024

EP300 restores the glycolytic activity and anti-tumor function of CD8 cytotoxic T cells in nasopharyngeal carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zhixiu Xia,Xiaoxu Ding,Chao Ji,Dabo Zhou,Xun Sun,Tiancong Liu

Journal of translational medicine 21:721 PubMed37838657

2023

Cancer stem cell-derived CHI3L1 activates the MAF/CTLA4 signaling pathway to promote immune escape in triple-negative breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Shufeng Ji,Hao Yu,Dan Zhou,Xulong Fan,Yan Duan,Yijiang Tan,Min Lang,Guoli Shao

Journal of gastrointestinal oncology 14:1669-1693 PubMed37720449

2023

Esophageal cancer stem cells reduce hypoxia-induced apoptosis by inhibiting the GRP78-perk-eIF2α-ATF4-CHOP pathway .

Applications

Unspecified application

Species

Unspecified reactive species

Ruijiang Lin,Minjie Ma,Biao Han,Ya Zheng,Yuping Wang,Yongning Zhou

Animals : an open access journal from MDPI 13: PubMed36611625

2022

Isolation and Identification of Bone Marrow Mesenchymal Stem Cells from Forest Musk Deer.

Applications

Unspecified application

Species

Unspecified reactive species

Weiqiang Luo,Yangyang Geng,Mengxi Gao,Mengting Cao,Junjian Wang,Jing Yang,Chenxuan Sun,Xingrong Yan

Bioengineered 13:3896-3910 PubMed35109743

2022

Ultrasound targeted microbubble destruction-mediated SOCS3 attenuates biological characteristics and epithelial-mesenchymal transition (EMT) of breast cancer stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaojiang Tang,Na Hao,Yuhui Zhou,Yang Liu

View all publications

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