AB95700

PE Anti-CD90 / Thy1 antibody [5E10]

Name: Anti-CD90 / Thy1 PE antibody [5E10] (ab95700) Mouse monoclonal IgG1 | Abcam
Brand: Abcam Limited
SKU: AB95700
Price: 175 USD
Availability: InStock

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(6 Publications)

Mouse Monoclonal CD90 / Thy1 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Cell preparation containing THY1 protein.

View Alternative Names

CD90, Thy-1 membrane glycoprotein, CDw90, Thy-1 antigen, THY1

1 Images

Flow Cytometry - PE Anti-CD90 / Thy1 antibody [5E10] (AB95700)

Flow Cyt

Unknown

Flow Cytometry - PE Anti-CD90 / Thy1 antibody [5E10] (AB95700)

Flow cytometry staining of Human erythroleukemia (HEL) cells with Mouse IgG1 kappa Isotype Control PE (open histogram) or ab95700 (filled histogram). Total viable cells were used for analysis.

Unconjugated

Anti-CD90 / Thy1 antibody [5E10]
519 FITC

FITC Anti-CD90 / Thy1 antibody [5E10]
660 APC

APC Anti-CD90 / Thy1 antibody [5E10]
695 PerCP/Cy5.5®

PerCP/Cy5.5® Anti-CD90 / Thy1 antibody [5E10]
667 PE/Cy5®

PE/Cy5® Anti-CD90 / Thy1 antibody [5E10]
785 APC/Cy7®

APC/Cy7® Anti-CD90 / Thy1 antibody [5E10]
Biotin

Biotin Anti-CD90 / Thy1 antibody [5E10]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

5E10

Isotype

IgG1

Light chain type

kappa

Conjugation

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing THY1 protein. The exact immunogen used to generate this antibody is proprietary information.

P04216

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "5 µL for 10^6 Cells", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/pe-mouse-igg1-b11-6-isotype-control-ab91357'>ab91357</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.2 Preservative: 0.09% Sodium azide

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

CD90 also known as Thy1 is a glycoprotein with a molecular mass of approximately 25-37 kDa. It is highly conserved across species and found on the surface of various cell types including fibroblasts neurons and endothelial cells. CD90 is expressed in these cells in tissues such as the brain thymus and lungs. Researchers use anti-CD90 antibodies for detection often in combination with CD90 FITC in immunofluorescence assays. CD90 serves as a useful cell marker particularly in identifying mesenchymal stem cells (MSCs).

Biological function summary

CD90 plays a role in cell-cell and cell-matrix interactions contributing to cellular adhesion migration and signal transduction. It functions as part of a complex involving integrins which mediate its interaction with the extracellular matrix. This protein also influences T-cell activation reflecting its importance in immune response regulation. Its presence aids in modulating response to injury and promoting tissue repair due to its association with stem and progenitor cells.

Pathways

CD90 engagement affects focal adhesion and MAPK signaling pathways. It interacts with integrins like αvβ3 and α5β1 influencing cell movement and proliferation processes. CD90 involvement in these pathways allows it to regulate responses important for cell survival and communication within various tissues. These interactions highlight the protein's role in maintaining cellular homeostasis and regulating physiological processes.

CD90 has associations with fibrosis and cancer. In fibrotic conditions CD90 expression affects fibroblast activity influencing tissue scarring in organs such as the liver and lungs. In cancer CD90 modifies tumor progression and metastasis by impacting cell adhesion and migration with connections to proteins like TGF-beta which further drive these processes. Understanding CD90 in disease contexts facilitates the development of therapeutic strategies aimed at modulating its activity.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

See full target information THY1

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Turkish journal of biology = Turk biyoloji dergisi 46:400-413 PubMed37529007

2022

The investigation of diverse physiological and therapeutic impact of cellular-based products derived from human cumulus cells.

Applications

Unspecified application

Species

Unspecified reactive species

Derya Burukçu,Sema Yilmaz,Oya Alagöz,Cumhur Kaan Yaltirik,Erkut Attar,Fikrettin Şahin,Esra Aydemir

Bioengineered 12:12891-12904 PubMed34784837

2021

MiR-455-5p upregulation in umbilical cord mesenchymal stem cells attenuates endometrial injury and promotes repair of damaged endometrium via Janus kinase/signal transducer and activator of transcription 3 signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Dongyan Sun,Zhihe Jiang,Yanling Chen,Di Shang,Pan Miao,Jian Gao

PloS one 15:e0242960 PubMed33270690

2020

Shear stress-exposed pulmonary artery endothelial cells fail to upregulate HSP70 in chronic thromboembolic pulmonary hypertension.

Applications

Unspecified application

Species

Unspecified reactive species

William Salibe-Filho,Thaís L S Araujo,Everton G Melo,Luiza B C T Coimbra,Monica S Lapa,Milena M P Acencio,Orival Freitas-Filho,Vera Luiza Capelozzi,Lisete Ribeiro Teixeira,Caio J C S Fernandes,Fabio Biscegli Jatene,Francisco R M Laurindo,Mario Terra-Filho

Cell transplantation 26:867-878 PubMed28105983

2017

Effect of Bone Marrow Aspirate Concentrate-Platelet-Rich Plasma on Tendon-Derived Stem Cells and Rotator Cuff Tendon Tear.

Applications

Unspecified application

Species

Unspecified reactive species

Sun Jeong Kim,Da Hyun Song,Jong Wook Park,Silvia Park,Sang Jun Kim

Blood 83:2410-7 PubMed7513197

1994

Thy-1 expression is linked to functional properties of primitive hematopoietic progenitor cells from human umbilical cord blood.

Applications

Unspecified application

Species

Unspecified reactive species

H Mayani,P M Lansdorp

The Journal of experimental medicine 177:1331-42 PubMed7683034

1993

Expression of Thy-1 on human hematopoietic progenitor cells.

Applications

Unspecified application

Species

Unspecified reactive species

W Craig,R Kay,R L Cutler,P M Lansdorp

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

PE Anti-CD90 / Thy1 antibody [5E10]

Flow Cytometry - PE Anti-CD90 / Thy1 antibody [5E10] (AB95700)

Related conjugates and formulations (7)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (6)

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