Mouse Monoclonal CD31 antibody - conjugated to Cy5®. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing CD31 protein.
Images
![Flow Cytometry - PE/Cy5® Anti-CD31 antibody [MEM05] (AB233642), expandable thumbnail](https://content.abcam.com/products/images/pe-cy5-cd31-antibody-mem05-ab233642--flow-cytometry-img75613.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - PE/Cy5® Anti-CD31 antibody [MEM05] (AB233642)")
Publications
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- Stem cell research & therapy 9:3482018Long non-coding RNA HIF1A-AS2 facilitates adipose-derived stem cells (ASCs) osteogenic differentiation through miR-665/IL6 axis via PI3K/Akt signaling pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRuoyu Wu et. al.PubMed 30545407
Key facts
- Isotype
IgG1
- Host species
Mouse
- Conjugation
Cy5®
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
Liquid
- Clonality
Monoclonal
Immunogen
- Cell preparation containing CD31 protein. The exact immunogen used to generate this antibody is proprietary information. Database link P16284
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Human | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 4 µL for 106 Cells | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Version
8 products for Alternative Product
Target data
Function
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed:19342684, PubMed:17580308). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed:19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed:27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed:17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed:12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed:12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed:18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed:18672896). Induces susceptibility to atherosclerosis (By similarity).Isoform Delta15Does not protect against apoptosis.
Alternative names
Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1
Recommended products
Mouse Monoclonal CD31 antibody - conjugated to Cy5®. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing CD31 protein.
Key facts
- Isotype
IgG1
- Host species
Mouse
- Conjugation
Cy5®
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
Liquid
- Clonality
Monoclonal
- Immunogen
- Cell preparation containing CD31 protein. The exact immunogen used to generate this antibody is proprietary information. Database link P16284
- Clone number
MEM05
- Purification technique
Size-exclusion chromatography
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate long-term storage conditions
+4°C
- Storage information
Store in the dark
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
![Flow Cytometry - PE/Cy5® Anti-CD31 antibody [MEM05] (ab233642), expandable thumbnail](https://content.abcam.com/products/images/pe-cy5-cd31-antibody-mem05-ab233642--flow-cytometry-img75613.jpg "Flow Cytometry - PE/Cy5® Anti-CD31 antibody [MEM05] (ab233642)")
Flow Cytometry - PE/Cy5® Anti-CD31 antibody [MEM05] (ab233642)
Surface staining of human peripheral blood labeling CD31 with ab233642.
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