Mouse Monoclonal CD41 antibody - conjugated to PE/Cy5®. Suitable for Flow Cyt and reacts with Human samples. Immunogen corresponding to Cell preparation containing ITGA2B protein.
Images
![Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450), expandable thumbnail](https://content.abcam.com/products/images/pe-cy5-cd41-antibody-mem-06-ab233450--flow-cytometry-img439004.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450)")
![Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450), expandable thumbnail](https://content.abcam.com/products/images/pe-cy5-cd41-antibody-mem-06-ab233450--flow-cytometry-img439005.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450)")
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Conjugation
- PE/Cy5®
- Excitation/Emission
- Ex: 496nm, Em: 667nm
- Storage buffer
pH: 7.4
Preservative: 0.0975% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Cell preparation containing ITGA2B protein. The exact immunogen used to generate this antibody is proprietary information. Database link P08514
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Human | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 4 µL for 106 Cells | Notes - |
Associated Products
Select an associated product type
6 products for Alternative Product
Target data
Function
Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed:9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity).
Alternative names
CD41, GP2B, ITGAB, ITGA2B, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb
Recommended products
Mouse Monoclonal CD41 antibody - conjugated to PE/Cy5®. Suitable for Flow Cyt and reacts with Human samples. Immunogen corresponding to Cell preparation containing ITGA2B protein.
Key facts
- Isotype
- IgG1
- Host species
- Mouse
- Conjugation
- PE/Cy5®
- Excitation/Emission
- Ex: 496nm, Em: 667nm
- Storage buffer
pH: 7.4
Preservative: 0.0975% Sodium azide
Constituents: PBS- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Cell preparation containing ITGA2B protein. The exact immunogen used to generate this antibody is proprietary information. Database link P08514
- Clone number
- MEM-06
- Purification technique
- Size-exclusion chromatography
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Storage information
- Store in the dark
Notes
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
![Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (ab233450), expandable thumbnail](https://content.abcam.com/products/images/pe-cy5-cd41-antibody-mem-06-ab233450--flow-cytometry-img439004.jpg "Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (ab233450)")
Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (ab233450)
Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD41 (MEM-06) PE-Cy™5 antibody (4 µl reagent / 100 µl of peripheral whole blood).
![Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (ab233450), expandable thumbnail](https://content.abcam.com/products/images/pe-cy5-cd41-antibody-mem-06-ab233450--flow-cytometry-img439005.jpg "Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (ab233450)")
Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (ab233450)
Separation of human CD41 positive thrombocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD41 (MEM-06) PE-Cy™5 antibody (4 µl reagent / 100 µl of peripheral whole blood).
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com