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AB233450

PE/Cy5® Anti-CD41 antibody [MEM-06]

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(1 Publication)

Mouse Monoclonal CD41 antibody - conjugated to PE/Cy5®. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing ITGA2B protein.

View Alternative Names

CD41, GP2B, ITGAB, ITGA2B, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb

2 Images
Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450)

Separation of human CD41 positive thrombocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD41 (MEM-06) PE-Cy™5 antibody (4 µl reagent / 100 µl of peripheral whole blood).

Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy5® Anti-CD41 antibody [MEM-06] (AB233450)

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD41 (MEM-06) PE-Cy™5 antibody (4 µl reagent / 100 µl of peripheral whole blood).

  • Unconjugated

    Anti-CD41 antibody [MEM-06]

  • 578 PE

    PE Anti-CD41 antibody [MEM-06]

  • 519 FITC

    FITC Anti-CD41 antibody [MEM-06]

  • Biotin

    Biotin Anti-CD41 antibody [MEM-06]

  • 660 APC

    APC Anti-CD41 antibody [MEM-06]

  • 778 PE/Cy7®

    PE/Cy7® Anti-CD41 antibody [MEM-06]

  • 723 Alexa Fluor® 700

    Alexa Fluor® 700 Anti-CD41 antibody [MEM-06]

  • 675 PerCP

    PerCP Anti-CD41 antibody [MEM-06]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-06

Isotype

IgG1

Conjugation

PE/Cy5®

Excitation/Emission

Ex: 496nm, Em: 667nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing ITGA2B protein. The exact immunogen used to generate this antibody is proprietary information.

P08514

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "4 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }

Product details

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.

Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Storage buffer
pH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed : 9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity).
See full target information ITGA2B

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

World journal of clinical cases 9:2181-2191 PubMed33869594

2021

Iguratimod promotes transformation of mononuclear macrophages in elderly patients with rheumatoid arthritis by nuclear factor-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Sha Liu,Li-Ping Song,Rong-Bin Li,Le-Heng Feng,Hui Zhu
View all publications

Product promise

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