AB25534

PE/Cy5® Anti-IL-2 Receptor alpha antibody [7D4]

Name: Anti-IL-2 Receptor alpha PE/Cy5® antibody [7D4] (ab25534) IgM | Abcam
Brand: Abcam Limited
SKU: AB25534
Price: 535 USD
Availability: InStock

Be the first to review this product! Submit a review

(4 Publications)

Rat Monoclonal IL2RA antibody - conjugated to PE/Cy5®. Suitable for IP, Flow Cyt and reacts with Mouse samples. Cited in 4 publications. Immunogen corresponding to Cell preparation containing Il2ra protein.

View Alternative Names

CD25, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55

1 Images

Flow Cytometry - PE/Cy5® Anti-IL-2 Receptor alpha antibody [7D4] (AB25534)

Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy5® Anti-IL-2 Receptor alpha antibody [7D4] (AB25534)

Con-A stimulated BALB/c mouse splenocytes were stained with Rat Anti- Mouse CD25-PE/Cy5 (ab25534). The grey peak represents an isotype control. The purple peak represents the positive dataset.

660 APC

APC Anti-IL-2 Receptor alpha antibody [7D4]

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

7D4

Isotype

IgM

Light chain type

kappa

Conjugation

PE/Cy5®

Excitation/Emission

Ex: 496nm, Em: 667nm

Carrier free

Reacts with

Mouse

Applications

IP, Flow Cyt

applications

Immunogen

Cell preparation containing Il2ra protein. The exact immunogen used to generate this antibody is proprietary information.

P01590

Epitope

ab25534 reacts with an epitope between amino acids 125 and 212.

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>" } } }

style

left-column

Product details

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.

style

left-column

Properties and storage information

Form

Liquid

Purity

IgM fraction

Storage buffer

pH: 7.1 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose, 0.2% Gelatin

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Store in the dark

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

See full target information Il2ra

style

left-column

Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Journal of immunology (Baltimore, Md. : 1950) 147:2970-7 PubMed1717581

1991

Structure-function study of the p55 subunit of murine IL-2 receptor by epitope mapping.

Applications

Unspecified application

Species

Unspecified reactive species

F Lorenzo,C Jaulin,N Vita,P Froussard,P Ferrara,D L Jankovic,J Theze

European journal of immunology 17:929-35 PubMed2440696

1987

Monoclonal antibodies identify three epitope clusters on the mouse p55 subunit of the interleukin 2 receptor: relationship to the interleukin 2-binding site.

Applications

Unspecified application

Species

Unspecified reactive species

J L Moreau,M Nabholz,T Diamantstein,T Malek,E Shevach,J Thèze

Journal of immunology (Baltimore, Md. : 1950) 133:1976-82 PubMed6432904

1984

The murine IL 2 receptor. II. Monoclonal anti-IL 2 receptor antibodies as specific inhibitors of T cell function in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

T R Malek,G Ortega,J P Jakway,C Chan,E M Shevach

Journal of immunology (Baltimore, Md. : 1950) 133:1970-5 PubMed6206144

1984

The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells.

Applications

Unspecified application

Species

Unspecified reactive species

G Ortega,R J Robb,E M Shevach,T R Malek

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

PE/Cy5® Anti-IL-2 Receptor alpha antibody [7D4]

Flow Cytometry - PE/Cy5® Anti-IL-2 Receptor alpha antibody [7D4] (AB25534)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Epitope

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (4)

Alternative Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Complementary Products

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise