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AB233660

PE/Cy7® Anti-CD4 antibody [MEM-241]

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(3 Publications)

Mouse Monoclonal CD4 antibody - conjugated to PE/Cy7®. Suitable for Flow Cyt and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CD4.

View Alternative Names

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

3 Images
Flow Cytometry - PE/Cy7® Anti-CD4 antibody [MEM-241] (AB233660)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy7® Anti-CD4 antibody [MEM-241] (AB233660)

Surface staining of human peripheral blood cells with ab233660.

Flow Cytometry - PE/Cy7® Anti-CD4 antibody [MEM-241] (AB233660)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy7® Anti-CD4 antibody [MEM-241] (AB233660)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab233660 (concentration in sample 0.33 µg/ml).

Flow Cytometry - PE/Cy7® Anti-CD4 antibody [MEM-241] (AB233660)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy7® Anti-CD4 antibody [MEM-241] (AB233660)

Flow cytometry surface staining pattern of human peripheral whole blood stained using ab233660 (concentration in sample 0.33 µg/ml).

  • 660 APC

    APC Anti-CD4 antibody [MEM-241]

  • 785 APC/Cy7®

    APC/Cy7® Anti-CD4 antibody [MEM-241]

  • 723 Alexa Fluor® 700

    Alexa Fluor® 700 Anti-CD4 antibody [MEM-241]

  • Biotin

    Biotin Anti-CD4 antibody [MEM-241]

  • 519 FITC

    FITC Anti-CD4 antibody [MEM-241]

  • 578 PE

    PE Anti-CD4 antibody [MEM-241]

  • 675 PerCP

    PerCP Anti-CD4 antibody [MEM-241]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-241

Isotype

IgG1

Light chain type

kappa

Conjugation

PE/Cy7®

Excitation/Emission

Ex: 565nm, Em: 778nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Fragment Protein within Human CD4. The exact immunogen used to generate this antibody is proprietary information.

P01730

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "4 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

BMC infectious diseases 24:229 PubMed38378486

2024

Chlamydia trachomatis enhances HPV persistence through immune modulation.

Applications

Unspecified application

Species

Unspecified reactive species

Yingying Lu,Qi Wu,Li Wang,Lingting Ji

Translational oncology 40:101831 PubMed38039947

2023

Silencing of PD-1 combined with EBV-specific killer T cells for the treatment of EBV-associated B lymphoma.

Applications

Unspecified application

Species

Unspecified reactive species

Jiaping Wang,Zhijuan Xu,Yanli Lai,Yanli Zhang,Ping Zhang,Qitian Mu,Shujun Yang,Yongcheng Sun,Lixia Sheng,Guifang Ouyang

World journal of clinical cases 9:2181-2191 PubMed33869594

2021

Iguratimod promotes transformation of mononuclear macrophages in elderly patients with rheumatoid arthritis by nuclear factor-κB pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Sha Liu,Li-Ping Song,Rong-Bin Li,Le-Heng Feng,Hui Zhu
View all publications
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Product promise

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