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AB234275

PE/Cy7® Anti-Fas antibody [LT95]

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(1 Publication)

Mouse Monoclonal Fas antibody - conjugated to PE/Cy7®. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing FAS protein.

View Alternative Names

CD95, APT1, FAS1, TNFRSF6, FAS, Tumor necrosis factor receptor superfamily member 6, Apo-1 antigen, Apoptosis-mediating surface antigen FAS, FASLG receptor

1 Images
Flow Cytometry - PE/Cy7® Anti-Fas antibody [LT95] (AB234275)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE/Cy7® Anti-Fas antibody [LT95] (AB234275)

Flow Cytometry analysis of human peripheral blood labeling Fas with ab234275. Surface staining. Gated on leukocytes.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

LT95

Isotype

IgG1

Conjugation

PE/Cy7®

Excitation/Emission

Ex: 565nm, Em: 778nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing FAS protein. The exact immunogen used to generate this antibody is proprietary information.

P25445

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "4 µL for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }
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Product details

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
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Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Purification notes
ab234275 is conjugated with tandem dye PE-Cy™7 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Storage buffer
pH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
See full target information FAS
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Developmental cell 57:2257-2272.e5 PubMed36182685

2022

Pluripotency factors are repurposed to shape the epigenomic landscape of neural crest cells.

Applications

Unspecified application

Species

Unspecified reactive species

Austin S Hovland,Debadrita Bhattacharya,Ana Paula Azambuja,Dimitrius Pramio,Jacqueline Copeland,Megan Rothstein,Marcos Simoes-Costa
View all publications
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Product promise

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