Mouse Monoclonal IGHG1 antibody - conjugated to Cy7®. Suitable for Flow Cyt and reacts with Human samples.
Images
![Flow Cytometry - PE/Cy7® Anti-IgG antibody [4A11] (AB205544), expandable thumbnail](https://content.abcam.com/products/images/pe-cy7-igg-antibody-4a11-ab205544--flow-cytometry-img83024.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - PE/Cy7® Anti-IgG antibody [4A11] (AB205544)")
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Conjugation
- Cy7®
- Excitation/Emission
- Ex: 743nm, Em: 767nm
- Storage buffer
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: 99% PBS, 0.2% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information. Database link P01857
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Human | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 4 µL for 106 Cells | Notes or 100 μl of whole blood |
Associated Products
Select an associated product type
1 product for Alternative Version
7 products for Alternative Product
Target data
Function
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Mediates IgG effector functions on monocytes triggering ADCC of virus-infected cells.
Alternative names
Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1
Recommended products
Mouse Monoclonal IGHG1 antibody - conjugated to Cy7®. Suitable for Flow Cyt and reacts with Human samples.
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Conjugation
- Cy7®
- Excitation/Emission
- Ex: 743nm, Em: 767nm
- Storage buffer
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: 99% PBS, 0.2% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information. Database link P01857
- Clone number
- 4A11
- Purification technique
- Size-exclusion chromatography
- Specificity
ab205544 reacts with Fab fragment of Human IgG.
- Concentration
- Purification notes
The ab205544 conjugate is made from highly purified antibodies (>95% by SDS-PAGE).
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- +4°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Store in the dark
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Flow Cytometry - PE/Cy7® Anti-IgG antibody [4A11] (ab205544), expandable thumbnail](https://content.abcam.com/products/images/pe-cy7-igg-antibody-4a11-ab205544--flow-cytometry-img83024.jpg "Flow Cytometry - PE/Cy7® Anti-IgG antibody [4A11] (ab205544)")
Flow Cytometry - PE/Cy7® Anti-IgG antibody [4A11] (ab205544)
Flow Cytometry analysis of human peripheral blood cells labeling IgG with Anti-IgG antibody [4A11] (PE/Cy7 ®) (ab205544).
Downloads
Product protocols
- Visit the general protocols
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