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AB93566

PE Anti-Fas Ligand antibody [MFL3]

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(1 Publication)

Armenian hamster Monoclonal Fas Ligand antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 1 publication.

View Alternative Names

CD178, Apt1lg1, Cd95l, Fasl, gld, Tnfsf6, Faslg, Tumor necrosis factor ligand superfamily member 6, CD95 ligand, Fas antigen ligand, CD95-L, Fas ligand, FasL

1 Images
Flow Cytometry - PE Anti-Fas Ligand antibody [MFL3] (AB93566)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-Fas Ligand antibody [MFL3] (AB93566)

Surface staining of mouse Fas Ligand transfected cells with 0.5μg ab93566. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

  • Carrier free

    Anti-Fas Ligand antibody [MFL3] - Low endotoxin, Azide free

Key facts

Host species

Armenian hamster

Clonality

Monoclonal

Clone number

MFL3

Isotype

IgG

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.5-1 µg for 10^5-10^8 Cells", "FlowCyt-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.87% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed : 7511063). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed : 19794494, PubMed : 7532682). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed : 19794494). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed : 10779162). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity).. Tumor necrosis factor ligand superfamily member 6, soluble form. Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways (PubMed : 19794494). Can induce apoptosis but does not appear to be essential for this process (By similarity).. FasL intracellular domain. Cytoplasmic form induces gene transcription inhibition.
See full target information Faslg
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Nature 304:30-4 PubMed6866086

1983

A cell-surface molecule involved in organ-specific homing of lymphocytes.

Applications

Unspecified application

Species

Unspecified reactive species

W M Gallatin,I L Weissman,E C Butcher
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Product promise

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