Armenian hamster Monoclonal Fas Ligand antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Mouse samples.
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.87% Sodium chloride
Flow Cyt | |
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Mouse | Tested |
Species | Dilution info | Notes |
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Species Mouse | Dilution info 0.50000-1.00000 µg for 105-108 Cells | Notes - |
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Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells (PubMed:7511063). Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development (PubMed:19794494, PubMed:7532682). Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses (PubMed:19794494). TNFRSF6/FAS-mediated apoptosis has also a role in the induction of peripheral tolerance (PubMed:10779162). Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis (By similarity). Tumor necrosis factor ligand superfamily member 6, soluble form. Induces FAS-mediated activation of NF-kappa-B, initiating non-apoptotic signaling pathways (PubMed:19794494). Can induce apoptosis but does not appear to be essential for this process (By similarity). FasL intracellular domain. Cytoplasmic form induces gene transcription inhibition.
CD178, Apt1lg1, Cd95l, Fasl, gld, Tnfsf6, Faslg, Tumor necrosis factor ligand superfamily member 6, CD95 ligand, Fas antigen ligand, CD95-L, Fas ligand, FasL
Armenian hamster Monoclonal Fas Ligand antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Mouse samples.
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: PBS, 0.87% Sodium chloride
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Surface staining of mouse Fas Ligand transfected cells with 0.5μg ab93566. Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.
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