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AB25553

PE Anti-ICAM1 antibody [YN1/1.7.4]

5

(1 Review)

|

(4 Publications)

Rat Monoclonal ICAM1 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 4 publications. Immunogen corresponding to Cell preparation containing Icam1 protein.

View Alternative Names

CD54, Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor, ICAM1

1 Images
Flow Cytometry - PE Anti-ICAM1 antibody [YN1/1.7.4] (AB25553)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-ICAM1 antibody [YN1/1.7.4] (AB25553)

Flow cytometric analysis of C57BL/6 mouse splenocytes labelling ICAM1 with ab25553 at 0.1 μg/106 cells and labelling CD49b with a Rat Anti-Mouse CD49b-FITC antibody.

  • 660 APC

    APC Anti-ICAM1 antibody [YN1/1.7.4]

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

YN1/1.7.4

Isotype

IgG2b

Light chain type

kappa

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing Icam1 protein. The exact immunogen used to generate this antibody is proprietary information.

P13597

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 16% Sucrose
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL : ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing a calibrated system to namely adjust T-cell killing to the antigen stimulation strength (PubMed : 3086451, PubMed : 3340213, PubMed : 38195629). Also functions as a ligand receptor of the signaling receptor ITGAM : ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed : 1980124). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (PubMed : 17875742). Promotes cell aggregation in epithelial cells through interaction with MUC1 (PubMed : 11173916).. (Microbial infection) Acts as a receptor for major receptor group rhinovirus A-B capsid proteins.. (Microbial infection) Acts as a receptor for Coxsackievirus A21 capsid proteins.. (Microbial infection) Upon Kaposi's sarcoma-associated herpesvirus/HHV-8 infection, is degraded by viral E3 ubiquitin ligase MIR2, presumably to prevent lysis of infected cells by cytotoxic T-lymphocytes and NK cell.
See full target information ICAM1
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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Journal of immunology (Baltimore, Md. : 1950) 157:5016-21 PubMed8943409

1996

The roles of CD11/CD18 and ICAM-1 in acute Pseudomonas aeruginosa-induced pneumonia in mice.

Applications

Unspecified application

Species

Unspecified reactive species

L Qin,W M Quinlan,N A Doyle,L Graham,J E Sligh,F Takei,A L Beaudet,C M Doerschuk

Journal of immunology (Baltimore, Md. : 1950) 150:2203-10 PubMed8095510

1993

Inhibition of cell adhesion by microspheres coated with recombinant soluble intercellular adhesion molecule-1.

Applications

Unspecified application

Species

Unspecified reactive species

C A Welder,D H Lee,F Takei

The EMBO journal 8:2889-96 PubMed2573511

1989

Molecular cloning of murine intercellular adhesion molecule (ICAM-1).

Applications

Unspecified application

Species

Unspecified reactive species

K J Horley,C Carpenito,B Baker,F Takei

Journal of immunology (Baltimore, Md. : 1950) 134:1403-7 PubMed2981916

1985

Inhibition of mixed lymphocyte response by a rat monoclonal antibody to a novel murine lymphocyte activation antigen (MALA-2).

Applications

Unspecified application

Species

Unspecified reactive species

F Takei
View all publications
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Product promise

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