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AB318346

PE Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

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Rabbit Recombinant Monoclonal KDM4A / JHDM3A / JMJD2A antibody - conjugated to PE.

View Alternative Names

JHDM3A, JMJD2, JMJD2A, KIAA0677, KDM4A, Lysine-specific demethylase 4A, JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A

  • Carrier free

    Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466] - BSA and Azide free

  • Unconjugated

    Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

  • 775 Alexa Fluor® 750

    Alexa Fluor® 750 Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

  • 519 Alexa Fluor® 488

    Alexa Fluor® 488 Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

  • 660 APC

    APC Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

  • 617 Alexa Fluor® 594

    Alexa Fluor® 594 Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

  • 565 Alexa Fluor® 555

    Alexa Fluor® 555 Anti-KDM4A / JHDM3A / JMJD2A antibody [EPR18466]

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR18466

Isotype

IgG

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Applications

Antibody Labelling, Target Binding Affinity

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

IHC application is recommended for human and rat.

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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

How are conjugated primary antibodies validated?
This conjugated primary antibody is released using a quantitative quality control method that evaluates binding affinity post-conjugation and efficiency of antibody labeling.
For suitable applications and species reactivity, please refer to the unconjugated version of this clone.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code (PubMed : 26741168). Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.. Isoform 2. Crucial for muscle differentiation, promotes transcriptional activation of the Myog gene by directing the removal of repressive chromatin marks at its promoter. Lacks the N-terminal demethylase domain.
See full target information KDM4A
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Complementary Products

Assay Kits

AB113461

KDM4/JMJD2 Activity Quantification Assay Kit (Colorimetric)

Functional Studies - KDM4/JMJD2 Activity Quantification Assay Kit (Colorimetric) (AB113461)

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Proteins & Peptides

AB125541

Recombinant Human KDM4A / JHDM3A / JMJD2A protein

SDS-PAGE - Recombinant Human KDM4A / JHDM3A / JMJD2A protein (AB125541)

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com