PE Anti-NCAM1 antibody [MEM-188]
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(4 Publications)
Mouse Monoclonal NCAM1 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human, Mouse, Monkey samples. Cited in 4 publications. Immunogen corresponding to Cell preparation containing NCAM1 protein.
View Alternative Names
CD56, NCAM, NCAM1, Neural cell adhesion molecule 1, N-CAM-1, NCAM-1
- Flow Cyt
Supplier Data
Flow Cytometry - PE Anti-NCAM1 antibody [MEM-188] (AB18277)
Separation of human CD56 positive CD3 negative NK cells (red-filled) from CD56 negative CD3 positive T cells (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using ab18277 (20 µl reagent / 100 µl of peripheral whole blood).
- Flow Cyt
Supplier Data
Flow Cytometry - PE Anti-NCAM1 antibody [MEM-188] (AB18277)
Flow cytometry multicolor surface staining pattern of human lymphocytes stained using anti-human CD3 (UCHT1) APC antibody (10 µl reagent / 100 µl of peripheral whole blood) and ab18277 (20 µl reagent / 100 µl of peripheral whole blood).
Related conjugates and formulations (6)
Reactivity data
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
NCAM1 influences neuronal growth survival and synaptic plasticity. This protein is part of the immunoglobulin superfamily and contributes to dynamic interactions during development. NCAM1 exists on cell membranes assisting in the formation and maintenance of tissue structures. In particular cell adhesion molecule CAL53 interacts with NCAM1 highlighting its involvement in synaptic connections. Additionally NCAM1 impacts cellular migration and differentiation particularly in myogenic processes involving MY31's pathway.
Pathways
The NCAM1 protein participates in the MAPK signaling pathway and the PI3K/AKT pathway both essential in cellular growth and survival. NCAM1 acts alongside ERIC1 aiding in the transduction of signals that regulate cytoskeletal rearrangement. These pathways influence cellular communication and responses to external stimuli further enhancing tissue development and regeneration mechanisms.
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Publications (4)
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Proceedings of the National Academy of Sciences of the United States of America 120:e2205371120 PubMed36595695
2023
Applications
Unspecified application
Species
Unspecified reactive species
NPJ breast cancer 8:78 PubMed35780131
2022
Applications
Unspecified application
Species
Unspecified reactive species
Nucleic acids research 46:7686-7700 PubMed29931089
2018
Applications
Unspecified application
Species
Unspecified reactive species
PloS one 9:e99819 PubMed24932758
2014
Applications
Flow Cyt
Species
Mouse
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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