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AB200558

PE Anti-Siglec 7 antibody [6-434]

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(2 Publications)

Mouse Monoclonal Siglec 7 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing SIGLEC7 protein.

View Alternative Names

CD328, AIRM1, SIGLEC7, Sialic acid-binding Ig-like lectin 7, Siglec-7, Adhesion inhibitory receptor molecule 1, CDw328, D-siglec, QA79 membrane protein, p75, AIRM-1

1 Images
Flow Cytometry - PE Anti-Siglec 7 antibody [6-434] (AB200558)
  • Flow Cyt

Supplier Data

Flow Cytometry - PE Anti-Siglec 7 antibody [6-434] (AB200558)

Flow cytometry analysis of Siglec 7 in human peripheral blood with ab200558.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6-434

Isotype

IgG1

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing SIGLEC7 protein. The exact immunogen used to generate this antibody is proprietary information.

Q9Y286

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "10 µL for 10^6 Cells", "FlowCyt-species-notes": "<p>or 10 μl / 100 μl of whole blood</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Purification notes
ab200558 is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Storage buffer
pH: 7.4 Preservative: 0.098% Sodium azide Constituents: PBS, 0.2% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
See full target information SIGLEC7
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Protein science : a publication of the Protein Society 33:e4859 PubMed38145972

2023

Dynamic proximity interaction profiling suggests that YPEL2 is involved in cellular stress surveillance.

Applications

Unspecified application

Species

Unspecified reactive species

Gizem Turan,Çağla Ece Olgun,Hazal Ayten,Pelin Toker,Annageldi Ashyralyyev,Büşra Savaş,Ezgi Karaca,Mesut Muyan

Virology journal 19:68 PubMed35413989

2022

Increased expression of TIGIT and KLRG1 correlates with impaired CD56 NK cell immunity in HPV16-related cervical intraepithelial neoplasia.

Applications

Unspecified application

Species

Unspecified reactive species

You Nie,Dandan Liu,Wen Yang,Yazhuo Li,Lihua Zhang,Xia Cheng,Ruyu Chen,Bingbing Yuan,Guangzheng Zhang,Hongwei Wang
View all publications
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