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AB95812

PE Anti-Thy1.1 antibody [HIS51]

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(3 Publications)

Mouse Monoclonal CD90 / Thy1 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Rat samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing Thy1 protein.

View Alternative Names

CD90, Thy-1, Thy1, Thy-1 membrane glycoprotein, Thy-1 antigen

1 Images
Flow Cytometry - PE Anti-Thy1.1 antibody [HIS51] (AB95812)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-Thy1.1 antibody [HIS51] (AB95812)

Flow cytometric analysis of rat splenocytes with 0.03 µg of Anti-Mouse/Rat CD90.1 PE (ab95812). Appropriate isotype controls were used (open histogram). Total viable cells were used for analysis.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

HIS51

Isotype

IgG2a

Light chain type

kappa

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Rat

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing Thy1 protein. The exact immunogen used to generate this antibody is proprietary information.

P01830

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.06 µg for 10^5-10^8 Cells", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/pe-mouse-igg2a-b12-8-isotype-control-ab91363'>ab91363</a> - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.</p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS, 0.87% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Thy1.1 also known as CD90 is a cell surface glycoprotein with a mass of approximately 25-35 kDa. This protein is expressed on a variety of cells including T cells stem cells neurons and fibroblasts. Thy1.1 is important in cell-cell and cell-matrix interactions playing a role in cell adhesion and signaling. It is an important marker used to identify different cell populations especially in murine models. Researchers often study Thy1.1 for its role in immunology and neuroscience due to its widespread expression across different tissues.
Biological function summary

The functions of Thy1.1 involve cell communication and signal transduction. Thy1.1 does not form a known complex but interacts with other molecules to influence the cellular environment. It is involved in processes such as apoptosis inflammation and fibrosis. The protein facilitates cell activation and differentiation by interacting with integrins and other surface molecules further affecting cellular responses.

Pathways

Thy1.1 substantially participates in signaling pathways such as the T-cell receptor (TCR) signaling pathway and fibrosis-related pathways. In the TCR signaling pathway Thy1.1 modulates T cell activation and proliferation. Within fibrosis Thy1.1 involvement affects extracellular matrix regulation and fibrosis progression. It associates with proteins such as integrins and fibronectin which are important in these pathways contributing to diverse cellular outcomes.

Thy1.1 shows connections to conditions like fibrosis and multiple sclerosis. In fibrosis Thy1.1 plays a role in the regulation of extracellular matrix deposition affecting tissue remodeling and repair. It interacts with proteins involved in fibrosis signaling such as transforming growth factor-beta (TGF-β). In the context of multiple sclerosis Thy1.1 expression impacts immune cell functions potentially influencing disease progression. Researchers study these associations to explore therapeutic strategies targeting Thy1.1-related pathways.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
See full target information Thy1

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

PloS one 20:e0330078 PubMed40924776

2025

Efficacy and mechanism of high-purity HAMCC combined with CGF in promoting the repair of radiation-induced skin and soft tissue damage.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaohao Hu,Anru Liang,Tongling Zhao,Yu Ling,Yanlin Wei,Yuer Zuo,Hongmian Li

BMC nephrology 23:413 PubMed36575400

2022

Ntrk1 promotes mesangial cell proliferation and inflammation in rat glomerulonephritis model by activating the STAT3 and p38/ERK MAPK signaling pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Xiongjun Dong,Yingchun Tang

Scientific reports 11:12973 PubMed34155263

2021

A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells.

Applications

Unspecified application

Species

Unspecified reactive species

Benjamin Lindner,Eva Martin,Monika Steininger,Aleksandra Bundalo,Martin Lenter,Johannes Zuber,Michael Schuler
View all publications

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