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AB269343

PE Anti-Thy1.2 antibody [1aG4/C5]

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Mouse Monoclonal CD90 / Thy1 antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Mouse samples. Immunogen corresponding to Cell preparation containing Thy1 protein.

View Alternative Names

CD90, Thy-1, Thy1, Thy-1 membrane glycoprotein, Thy-1 antigen

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Flow Cytometry - PE Anti-Thy1.2 antibody [1aG4/C5] (AB269343)
  • Flow Cyt

Unknown

Flow Cytometry - PE Anti-Thy1.2 antibody [1aG4/C5] (AB269343)

Flow cytometry analysis (surface staining) of murine splenocytes labeling Thy1.2 with ab269343.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

1aG4/C5

Isotype

IgG3

Conjugation

PE

Excitation/Emission

Ex: 480;565nm, Em: 578nm

Carrier free

No

Reacts with

Mouse

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing Thy1 protein. The exact immunogen used to generate this antibody is proprietary information.

P01831

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-2 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Store in the dark
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Thy1.2 also known as Thy-1 antigen or CD90 is a glycoprotein with a mass of approximately 25-35 kDa. It is expressed on the surface of many cell types including neurons thymocytes and fibroblasts. Thy1.2 is part of the immunoglobulin superfamily and plays a role in cell-cell interactions adhesion and signal transduction. Researchers often study Thy1.2 in the context of the mouse model as it is a well-defined target in murine immunology and neurobiology.
Biological function summary

The Thy1.2 protein influences cellular adhesion and migration processes. It does not form part of a known complex but regulates multiple interactions at the cellular membrane. In the nervous system Thy1.2 impacts neurite outgrowth and synapse formation. In the immune system it modulates T-cell activation and cytokine production. These actions make Thy1.2 integral to cellular communication and response mechanisms.

Pathways

Thy1.2 plays significant roles in signal transduction and cell adhesion pathways. It participates in the MAPK/ERK pathway which is important for cell growth and survival. Thy1.2 interacts closely with integrin proteins facilitating cell-matrix adhesion and signaling. This connection supports cellular processes that depend on environmental cues impacting both development and immune responses.

Thy1.2 shows significant associations with cancer and fibrosis. In cancer abnormal Thy1.2 expression or function can influence tumor growth and metastasis often in conjunction with other proteins such as integrins and CD44. In fibrosis Thy1.2 impacts fibroblast activity and extracellular matrix regulation leading to tissue remodeling. Studies explore how modulating Thy1.2 levels or function might offer therapeutic potential in these conditions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
See full target information Thy1
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