Mouse Monoclonal TNF Receptor I antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TNFRSF1A.
Images
![Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (AB270654), expandable thumbnail](https://content.abcam.com/products/images/pe-tnf-receptor-i-antibody-h398-ab270654--flow-cytometry-img59628.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (AB270654)")
![Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (AB270654), expandable thumbnail](https://content.abcam.com/products/images/pe-tnf-receptor-i-antibody-h398-ab270654--flow-cytometry-img92790.jpg/_jcr_content/renditions/webp-475.webp "Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (AB270654)")
Key facts
- Isotype
IgG2a
- Host species
Mouse
- Conjugation
PE
- Excitation/Emission
Ex: 480;565nm, Em: 578nm
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
Liquid
- Clonality
Monoclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human TNFRSF1A. Database link P19438
Reactivity data
Select an application| Flow Cyt | |
|---|---|
| Human | Tested |
Flow Cyt
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 10 µL for 106 Cells | Notes - |
Target data
Function
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Alternative names
Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, p55, p60, TNF-R1, TNF-RI, TNFR-I, TNFR1, TNFAR, TNFRSF1A
Recommended products
Mouse Monoclonal TNF Receptor I antibody - conjugated to PE. Suitable for Flow Cyt and reacts with Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human TNFRSF1A.
Key facts
- Isotype
IgG2a
- Host species
Mouse
- Conjugation
PE
- Excitation/Emission
Ex: 480;565nm, Em: 578nm
- Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: PBS- Form
Liquid
- Clonality
Monoclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human TNFRSF1A. Database link P19438
- Clone number
H398
- Purification technique
Size-exclusion chromatography
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
+4°C
- Storage information
Store in the dark
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
![Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (ab270654), expandable thumbnail](https://content.abcam.com/products/images/pe-tnf-receptor-i-antibody-h398-ab270654--flow-cytometry-img59628.jpg "Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (ab270654)")
Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (ab270654)
Flow cytometry analysis of human monocytes (red) and lymphocytes (black) cells labeling CD120a using ab270654. Concentration of 10 μl reagent/100μl peripheral whole blood.
![Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (ab270654), expandable thumbnail](https://content.abcam.com/products/images/pe-tnf-receptor-i-antibody-h398-ab270654--flow-cytometry-img92790.jpg "Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (ab270654)")
Flow Cytometry - PE Anti-TNF Receptor I antibody [H398] (ab270654)
Flow cytometric analysis of human peripheral whole blood cells labeling TNF Receptor I using ab270654. The concentration of 10 μl reagent/ 100μl of peripheral whole blood.
Downloads
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