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Rabbit Polyclonal PEPP2 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human PLEKHA5 aa 1-300.

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Images

Western blot - Anti-PEPP2 antibody (AB127741), expandable thumbnail

Key facts

Isotype

IgG

Host species

Rabbit

Storage buffer

pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human PLEKHA5 aa 1-300. The exact immunogen used to generate this antibody is proprietary information. Database link Q9HAU0

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested
Mouse
Predicted

Tested
Tested

Species

Human

Dilution info

1/500.00000 - 1/3000.00000

Notes

-

Predicted
Predicted

Species

Mouse

Dilution info

-

Notes

-

Alternative names

Recommended products

Rabbit Polyclonal PEPP2 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human PLEKHA5 aa 1-300.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Recombinant Fragment Protein within Human PLEKHA5 aa 1-300. The exact immunogen used to generate this antibody is proprietary information. Database link Q9HAU0
Purification technique

Affinity purification Immunogen

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

PEPP2 also known as Plasma Membrane Protein 2 has a mechanical function involving cellular signaling processes. This protein has a mass of approximately 45 kDa. Researchers observe PEPP2 expression mainly in tissues such as the brain and skeletal muscle where it plays a significant role. The protein contributes to the dynamics of cellular communication in these tissues influencing cellular responses to external stimuli.

Biological function summary

Within cellular settings PEPP2 appears to function as part of a larger signaling complex that modulates intracellular pathways. It interacts with multiple other signaling molecules to regulate processes like synaptic transmission and muscle contraction. The protein's activity is integral to proper cellular signaling ensuring that cells respond correctly to various physiological stimuli. Researchers have observed its involvement in maintaining cellular homeostasis and mediating cellular communication.

Pathways

Researchers have identified PEPP2's involvement in the synaptic signaling and muscle contraction pathways. It interacts with other proteins like Protein Kinase C (PKC) and calcium channels facilitating the transmission of signals across synapses and influencing muscle fiber response. This protein interaction is important for maintaining proper muscle function and nervous system signaling demonstrating PEPP2’s importance in these regulatory networks.

Associated diseases and disorders

Researchers have associated PEPP2 with neurological disorders and muscular dystrophies. Altered PEPP2 function can contribute to diseases like epilepsy where signaling pathways in the brain become dysregulated. In muscular dystrophies the protein's role in muscle contraction pathways suggests it might interact with proteins like dystrophin. These interactions could influence disease progression highlighting the need to understand its precise function in pathologies.

Product promise

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1 product image

  • Western blot - Anti-PEPP2 antibody (ab127741), expandable thumbnail

    Western blot - Anti-PEPP2 antibody (ab127741)

    7.5% SDS PAGE

    All lanes: Western blot - Anti-PEPP2 antibody (ab127741) at 1/1000 dilution

    All lanes: Jurkat whole cell lysate at 30 µg

    Predicted band size: 127 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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