Rabbit Polyclonal PEPP2 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human PLEKHA5 aa 1-300.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Liquid
Polyclonal
WB | |
---|---|
Human | Tested |
Mouse | Predicted |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Mouse | Dilution info - | Notes - |
KIAA1686, PEPP2, KIAA1686, PEPP2, PLEKHA5, Pleckstrin homology domain-containing family A member 5, PH domain-containing family A member 5, Phosphoinositol 3-phosphate-binding protein 2, PEPP-2
Rabbit Polyclonal PEPP2 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human PLEKHA5 aa 1-300.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 78.99% PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Liquid
Polyclonal
Affinity purification Immunogen
Blue Ice
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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This supplementary information is collated from multiple sources and compiled automatically.
PEPP2 also known as Plasma Membrane Protein 2 has a mechanical function involving cellular signaling processes. This protein has a mass of approximately 45 kDa. Researchers observe PEPP2 expression mainly in tissues such as the brain and skeletal muscle where it plays a significant role. The protein contributes to the dynamics of cellular communication in these tissues influencing cellular responses to external stimuli.
Within cellular settings PEPP2 appears to function as part of a larger signaling complex that modulates intracellular pathways. It interacts with multiple other signaling molecules to regulate processes like synaptic transmission and muscle contraction. The protein's activity is integral to proper cellular signaling ensuring that cells respond correctly to various physiological stimuli. Researchers have observed its involvement in maintaining cellular homeostasis and mediating cellular communication.
Researchers have identified PEPP2's involvement in the synaptic signaling and muscle contraction pathways. It interacts with other proteins like Protein Kinase C (PKC) and calcium channels facilitating the transmission of signals across synapses and influencing muscle fiber response. This protein interaction is important for maintaining proper muscle function and nervous system signaling demonstrating PEPP2’s importance in these regulatory networks.
Researchers have associated PEPP2 with neurological disorders and muscular dystrophies. Altered PEPP2 function can contribute to diseases like epilepsy where signaling pathways in the brain become dysregulated. In muscular dystrophies the protein's role in muscle contraction pathways suggests it might interact with proteins like dystrophin. These interactions could influence disease progression highlighting the need to understand its precise function in pathologies.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
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7.5% SDS PAGE
All lanes: Western blot - Anti-PEPP2 antibody (ab127741) at 1/1000 dilution
All lanes: Jurkat whole cell lysate at 30 µg
Predicted band size: 127 kDa
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