JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB225925

Anti-Peroxiredoxin Asp f3 antibody

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Polyclonal Peroxiredoxin Asp f3 antibody. Suitable for WB and reacts with Recombinant full length protein - Neosartorya fumigata samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Aspergillus fumigatus Af293 aspf3.

View Alternative Names

AFUA_6G02280, aspf3, Peroxiredoxin Asp f3, Prx, Thioredoxin peroxidase, Thioredoxin-dependent peroxiredoxin, TPx

1 Images
Western blot - Anti-Peroxiredoxin Asp f3 antibody (AB225925)
  • WB

Supplier Data

Western blot - Anti-Peroxiredoxin Asp f3 antibody (AB225925)

The recombinant protein used in this western blot is tagged with 6 His-SUMO tag at N-terminus.
Expected molecular weight of tag : 16kDa
Expected molecular weight of Peroxiredoxin Asp f3 : 19kDa

All lanes:

Western blot - Anti-Peroxiredoxin Asp f3 antibody (ab225925) at 1/500 dilution

Lane 1:

Recombinant protein 100 ng

Lane 2:

Recombinant protein 50 ng

Lane 3:

Recombinant protein 25 ng

Lane 4:

Recombinant protein 12.5 ng

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Observed band size: 35 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Neosartorya fumigata

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Aspergillus fumigatus Af293 aspf3.

O43099

style
left-column

Complementary Products

Primary Antibodies

AB225687

Anti-Major pollen allergen Bet v 1-A protein antibody

Western blot - Anti-Major pollen allergen Bet v 1-A protein antibody (AB225687)

  • 0
  • 0
Primary Antibodies

AB234682

Anti-Streptococcal Pyrogenic Exotoxin B antibody

Western blot - Anti-Streptococcal Pyrogenic Exotoxin B antibody (AB234682)

  • 0
  • 0
Primary Antibodies

AB133348

Anti-Peroxiredoxin 6 antibody [EPR3754]

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Peroxiredoxin 6 antibody [EPR3754] (AB133348)

  • 5
  • 2
Proteins & Peptides

AB186079

Recombinant Human TRIB1 protein

SDS-PAGE - Recombinant Human TRIB1 protein (AB186079)

  • 0
  • 0
style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Neosartorya fumigata": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant full length protein - Neosartorya fumigata": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Peroxiredoxin Asp f3 also known as Prx Asp f3 or Peroxiredoxin 3 is a protein with a molecular mass of approximately 27 kDa. This protein functions mechanically as an antioxidant enzyme. It catalyzes the reduction of hydrogen peroxide and organic hydroperoxides using thiol-containing molecules as electron donors. Peroxiredoxin Asp f3 mainly localizes in the mitochondria where it protects cells from oxidative stress.
Biological function summary

Peroxiredoxin Asp f3 serves in regulating cellular redox homeostasis. It operates within a complex system of antioxidant proteins that prevent damage from reactive oxygen species (ROS). Besides its catalytic role Peroxiredoxin Asp f3 participates in signaling pathways involved in cell proliferation and differentiation. The protein enables cells to adapt to changing oxidative environments which is significant for maintaining cellular health and function.

Pathways

Peroxiredoxin Asp f3 is integral to the antioxidant defense pathway and mitochondrial signaling pathway. Within these pathways Prx Asp f3 interacts with proteins like Thioredoxin forming a redox cycle critical for scavenging free radicals. The interaction between Peroxiredoxin Asp f3 and other redox-active proteins orchestrates a balanced oxidative state essential for preventing molecular damage and promoting cell survival.

Peroxiredoxin Asp f3 has significant connections to cancer and neurodegenerative diseases. Elevated levels of oxidative stress often linked to variations in Prx Asp f3 expression contribute to the pathogenesis of these conditions. Prx Asp f3 interacts with other proteins such as Glutathione Peroxidase in the progression of these diseases. Targeting Peroxiredoxin Asp f3 in therapeutic strategies could offer potential benefits by modulating oxidative stress and restoring cellular functions.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Required for virulence.
See full target information aspf3
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell division 20:3 PubMed39875985

2025

ZNF169 promotes thyroid cancer progression via upregulating FBXW10.

Applications

Unspecified application

Species

Unspecified reactive species

Wen Luo,Qiyu Xiao,Ying Fu
View all publications
style
left-column
style
left-column
style
right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com