Anti-Peroxiredoxin Asp f3 antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

Peroxiredoxin Asp f3 also known as Prx Asp f3 or Peroxiredoxin 3 is a protein with a molecular mass of approximately 27 kDa. This protein functions mechanically as an antioxidant enzyme. It catalyzes the reduction of hydrogen peroxide and organic hydroperoxides using thiol-containing molecules as electron donors. Peroxiredoxin Asp f3 mainly localizes in the mitochondria where it protects cells from oxidative stress.

Biological function summary

Peroxiredoxin Asp f3 serves in regulating cellular redox homeostasis. It operates within a complex system of antioxidant proteins that prevent damage from reactive oxygen species (ROS). Besides its catalytic role Peroxiredoxin Asp f3 participates in signaling pathways involved in cell proliferation and differentiation. The protein enables cells to adapt to changing oxidative environments which is significant for maintaining cellular health and function.

Pathways

Peroxiredoxin Asp f3 is integral to the antioxidant defense pathway and mitochondrial signaling pathway. Within these pathways Prx Asp f3 interacts with proteins like Thioredoxin forming a redox cycle critical for scavenging free radicals. The interaction between Peroxiredoxin Asp f3 and other redox-active proteins orchestrates a balanced oxidative state essential for preventing molecular damage and promoting cell survival.

Associated diseases and disorders

Peroxiredoxin Asp f3 has significant connections to cancer and neurodegenerative diseases. Elevated levels of oxidative stress often linked to variations in Prx Asp f3 expression contribute to the pathogenesis of these conditions. Prx Asp f3 interacts with other proteins such as Glutathione Peroxidase in the progression of these diseases. Targeting Peroxiredoxin Asp f3 in therapeutic strategies could offer potential benefits by modulating oxidative stress and restoring cellular functions.