Anti-Phospholipase c eta 1 antibody
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(2 Publications)
Rabbit Polyclonal Phospholipase c eta 1 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PLCH1 aa 1-300.
View Alternative Names
KIAA1069, PLCL3, PLCH1, Phosphoinositide phospholipase C-eta-1, Phospholipase C-eta-1, Phospholipase C-like protein 3, PLC-eta-1, PLC-L3
- WB
Unknown
Western blot - Anti-Phospholipase c eta 1 antibody (AB97751)
5% SDS PAGE
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Western blot - Anti-Phospholipase c eta 1 antibody (ab97751) at 1/500 dilution
All lanes:
293T whole cell lysate at 30 µg
Predicted band size: 189 kDa
false
Reactivity data
Properties and storage information
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Appropriate long-term storage conditions
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Phospholipase C eta 1 acts as a mediator of intracellular signal transduction. It participates in the regulation of ion channel activity by modulating calcium release from intracellular stores an important function in neural communication. Although not part of a classical multi-protein complex PLCη1 interacts with different signaling molecules and receptors influencing various signaling pathways. This regulatory control of calcium signaling underlies several physiological processes particularly in neurons.
Pathways
Phospholipase C eta 1 engages in the inositol phosphate pathway and the phosphatidylinositol signaling system. Its activity in these pathways leads to the generation of secondary messengers that mediate various downstream effects primarily through interactions with other key proteins including protein kinase C (PKC) and calcium channels. These pathways are critical for controlling neural signaling and plasticity therefore impacting neuron function and communication.
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Target data
Publications (2)
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Experimental & molecular medicine 57:872-887 PubMed40204881
2025
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Translational cancer research 9:2721-2733 PubMed35117631
2020
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Unspecified application
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Unspecified reactive species
Product promise
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