AB79960

Anti-Pig Albumin antibody

Name: Anti-Pig Albumin antibody (ab79960) | Abcam
Brand: Abcam Limited
SKU: AB79960
Price: 545 USD
Availability: InStock
Rating: 4 (2 reviews)

(2 Reviews)

(6 Publications)

Rabbit Polyclonal Albumin antibody. Suitable for ELISA, WB, IHC-P, RIA, EIA and reacts with Pig samples. Cited in 6 publications. Immunogen corresponding to Native Full Length Protein corresponding to Pig Albumin.

View Alternative Names

Albumin, ALB

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Pig

Applications

EIA, IHC-P, WB, ELISA, RIA

applications

Immunogen

Native Full Length Protein corresponding to Pig Albumin.

P08835

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Reactivity data

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Pig Albumin also known as serum albumin is a large protein with a molecular mass of approximately 67 kDa. This globular protein is mostly found in blood plasma where it plays a critical role in maintaining oncotic pressure and transporting different molecules. It is synthesized mainly in the liver and due to its high abundance it is an important component in regulating fluid balance throughout the body.

Biological function summary

Albumin plays several roles beyond transport. It has binding capabilities that allow it to carry hormones fatty acids and drugs acting as a carrier for a wide variety of substances. Albumin is not considered part of a complex; rather it functions independently in the bloodstream. Its ability to bind a diverse range of ligands comes from multiple binding sites making it a versatile protein in physiological processes.

Pathways

Albumin participates in the Renin-Angiotensin-Aldosterone System (RAAS) and other pathways linked to fluid balance and distribution. In the RAAS albumin helps in maintaining blood volume and pressure. It also interacts with proteins such as angiotensinogen contributing to vascular homeostasis. This involvement helps the body respond to changes in blood pressure and volume vital for cardiovascular health.

Albumin levels are markers in conditions like kidney disease and liver cirrhosis. Hypoalbuminemia a condition of low albumin levels often indicates issues with one of these organs. It is linked with modified levels of other plasma proteins like globulins and fibrinogen during disease states. Monitoring albumin provides important insights into the severity and progression of these conditions making it a critical protein in clinical diagnostics.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (By similarity). Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).

See full target information Albumin

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 24: PubMed37958567

2023

Proteomic Analyses Discern the Developmental Inclusion of Albumin in Pig Enamel: A New Model for Human Enamel Hypomineralization.

Applications

Unspecified application

Species

Unspecified reactive species

Ana Gil-Bona,Hakan Karaaslan,Baptiste Depalle,Rosalyn Sulyanto,Felicitas B Bidlack

Frontiers in medicine 9:925433 PubMed35847799

2022

Brain Histology and Immunohistochemistry After Resuscitation From Hemorrhagic Shock in Swine With Pre-Existing Atherosclerosis and Sodium Thiosulfate (NaSO) Treatment.

Applications

Unspecified application

Species

Unspecified reactive species

Nicole Denoix,Oscar McCook,Angelika Scheuerle,Thomas Kapapa,Andrea Hoffmann,Harald Gündel,Christiane Waller,Csaba Szabo,Peter Radermacher,Tamara Merz

Communications biology 4:1157 PubMed34620986

2021

Functional characterization of a bioengineered liver after heterotopic implantation in pigs.

Applications

Unspecified application

Species

Unspecified reactive species

Brett D Anderson,Erek D Nelson,DongJin Joo,Bruce P Amiot,Aleksandr A Katane,Alyssa Mendenhall,Benjamin G Steiner,Aron R Stumbras,Victoria L Nelson,R Noelle Palumbo,Thomas W Gilbert,Dominique S Davidow,Jeffrey J Ross,Scott L Nyberg

Scientific reports 10:13369 PubMed32770054

2020

Circulating GFAP and Iba-1 levels are associated with pathophysiological sequelae in the thalamus in a pig model of mild TBI.

Applications

Unspecified application

Species

Unspecified reactive species

Audrey D Lafrenaye,Stefania Mondello,Kevin K Wang,Zhihui Yang,John T Povlishock,Karen Gorse,Susan Walker,Ronald L Hayes,Patrick M Kochanek

Frontiers in neurology 11:649 PubMed32754111

2020

Cerebral Immunohistochemical Characterization of the HS and the Oxytocin Systems in a Porcine Model of Acute Subdural Hematoma.

Applications

Unspecified application

Species

Unspecified reactive species

Nicole Denoix,Tamara Merz,Sarah Unmuth,Andrea Hoffmann,Ester Nespoli,Angelika Scheuerle,Markus Huber-Lang,Harald Gündel,Christiane Waller,Peter Radermacher,Oscar McCook

International journal of molecular sciences 20: PubMed31817281

2019

Natural Flavonol, Myricetin, Enhances the Function and Survival of Cryopreserved Hepatocytes In Vitro and In Vivo.

Applications

Unspecified application

Species

Unspecified reactive species

Changhao Cui,Shin Enosawa,Hitomi Matsunari,Hiroshi Nagashima,Akihiro Umezawa

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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Anti-Pig Albumin antibody

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (6)

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