Rabbit Recombinant Monoclonal PPB1 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 19 publications.
Images
![Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--western-blot-img582.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602)")
![Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--western-blot-img2393.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img119300.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602)")
![Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--western-blot-img125680.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img71515.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (AB133602)")
Publications
Filter by
- Cell reports 39:1109622022Genetic encoding of an esophageal motor circuit.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTatiana C Coverdell,Ruei-Jen Abraham-Fan,Chen Wu,Stephen B G Abbott,John N CampbellPubMed 35705034
- Cells 11:2022Multifaceted Analyses of Isolated Mitochondria Establish the Anticancer Drug 2-Hydroxyoleic Acid as an Inhibitor of Substrate Oxidation and an Activator of Complex IV-Dependent State 3 Respiration.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKumudesh Mishra,Mária Péter,Anna Maria Nardiello,Guy Keller,Victoria Llado,Paula Fernandez-Garcia,Ulf D Kahlert,Dinorah Barasch,Ann Saada,Zsolt Török,Gábor Balogh,Pablo V Escriba,Stefano Piotto,Or KakhlonPubMed 35159387
- Bioengineered 12:9140-91492021Pathogenic mechanisms of preeclampsia with severe features implied by the plasma exosomal mirna profile.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZhirui Chen,Wen Zhang,Mengying Wu,Haixia Huang,Li Zou,Qingqing LuoPubMed 34696680
- The Journal of neuroscience : the official journal 40:8248-82612020Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTakao Kohno et. al.PubMed 33009002
- International journal of molecular medicine 46:546-5602020Placental exosomes isolated from urine of patients with gestational diabetes exhibit a differential profile expression of microRNAs across gestation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAna Sofía Herrera-Van Oostdam et. al.PubMed 32626972
- FASEB journal : official publication of the Federa 33:11925-119402019Meprin β induces activities of A disintegrin and metalloproteinases 9, 10, and 17 by specific prodomain cleavage.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRielana Wichert et. al.PubMed 31381863
- European spine journal : official publication of t 28:1977-19862019Asymmetric expression of GPR126 in the convex/concave side of the spine is associated with spinal skeletal malformation in adolescent idiopathic scoliosis population.Applications:Unspecified applicationReactive species:Unspecified reactive speciesEnjie Xu et. al.PubMed 31079250
- Advanced science (Weinheim, Baden-Wurttemberg, Ger 6:19001432019Aptameric Probe Specifically Binding Protein Heterodimer Rather Than Monomers.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTao Bing et. al.PubMed 31179220
- Journal of orthopaedic surgery and research 14:802019Macrophage inhibits the osteogenesis of fibroblasts in ultrahigh molecular weight polyethylene (UHMWPE) wear particle-induced osteolysis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPengfei Lei et. al.PubMed 30885228
- American journal of physiology. Heart and circulat 316:H889-H8992019TRPA1 channel contributes to myocardial ischemia-reperfusion injury.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDaniel J Conklin et. al.PubMed 30735434
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Abcam Recommends
Reactivity data
Select an application| IHC-P | ICC/IF | IP | Flow Cyt | WB | |
|---|---|---|---|---|---|
| Human | Tested | Not recommended | Not recommended | Not recommended | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/250 - 1/500 | Notes ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody. Perform heat-mediated antigen retrieval before commencing with IHC staining protocol. |
ICC/IF
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
IP
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
Flow Cyt
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/10000 - 1/50000 | Notes - |
Associated Products
Select an associated product type
9 products for Alternative Product
Target data
Function
Alkaline phosphatase that can hydrolyze various phosphate compounds.
Alternative names
PLAP, ALPP, Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, PLAP-1
Recommended products
Rabbit Recombinant Monoclonal PPB1 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 19 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR6141
- Purification technique
- Affinity purification Protein A
- Dissociation constant
- 5.1 x 10-11 M
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Stable for 12 months at -20°C
Notes
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
Placental alkaline phosphatase (PLAP) also known by names like alkaline phosphatase/PLAP protein or ALPP functions as an enzyme that removes phosphate groups from molecules. It typically appears in tissues such as the placenta and is known to be active during pregnancy. PLAP has a molecular mass of approximately 66 kDa. Normally found expressed in the placenta this enzyme shares similarities with other alkaline phosphatases but is distinct due to its specific expression and function during gestation.
- Biological function summary
PLAP shows importance in bone mineralization and fetal development. It participates in the hydrolysis of phosphate esters influencing nutrient availability and metabolism. PLAP is not a part of major protein complexes; however its enzymatic activity directly affects local phosphate concentrations which are critical for processes like bone formation and tissue regeneration during pregnancy.
- Pathways
PLAP expression and activity intersect significantly with phosphate metabolism and fetal development pathways. The alkaline phosphatase family plays central roles in these pathways and PLAP shares functions with other isoenzymes in the family such as the tissue nonspecific alkaline phosphatase. These enzymes regulate phosphate turnover and contribute to essential developmental processes.
- Associated diseases and disorders
PLAP connects primarily to certain types of cancers and gestational disorders. Elevated levels of PLAP link to testicular germ cell tumors and ovarian cancer where it serves as a biomarker. In gestational trophoblastic disease PLAP expression provides valuable diagnostic information. Interactions with proteins like hCG (human chorionic gonadotropin) also offer insights into potential disease mechanisms especially in reproductive health challenges.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
12 product images
![Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--western-blot-img582.jpg "Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
Lanes 1-4: Merged signal (red and green). Green - ab133602 observed at 70 kDa. Red - loading control, Anti-GAPDH antibody [6C5] - Loading Control ab8245 observed at 37 kDa.ab133602 Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] was shown to specifically react with Placental alkaline phosphatase (PLAP) in wild-type HeLa cells. Loss of signal was observed when knockout cell line Human ALPP (PLAP) knockout HeLa cell line ab261763 (knockout cell lysate Human ALPP (PLAP) knockout HeLa cell lysate ab256836) was used. Wild-type and Placental alkaline phosphatase (PLAP) knockout samples were subjected to SDS-PAGE. ab133602 and Anti-GAPDH antibody [6C5] - Loading Control (Anti-GAPDH antibody [6C5] - Loading Control ab8245) were incubated overnight at 4°C at 1 in 1000 dilution and 1 in 20000 dilution respectively. Blots were developed with Goat anti-Rabbit IgG H&L (IRDye® 800CW) preadsorbed (Goat anti-Rabbit IgG H&L (IRDye® 800CW) preadsorbed ab216773) and Goat anti-Mouse IgG H&L (IRDye® 680RD) preadsorbed (Goat anti-Mouse IgG H&L (IRDye® 680RD) preadsorbed ab216776) secondary antibodies at 1 in 10000 dilution for 1 hour at room temperature before imaging.
All lanes: Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602) at 1/1000 dilution
Lane 1: Wild-type HeLa cell lysate at 20 µg
Lane 2: ALPP knockout HeLa cell lysate at 20 µg
Lane 2: Western blot - Human ALPP (PLAP) knockout HeLa cell line (Human ALPP (PLAP) knockout HeLa cell line ab261763)
Lane 3: Human placenta tissue lysate at 20 µg
Lane 4: Human heart tissue lysate at 20 µg
Performed under reducing conditions.
Predicted band size: 58 kDa
Observed band size: 70 kDa
![Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--western-blot-img2393.jpg "Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
Lanes 1-4: Merged signal (red and green). Green - ab133602 observed at 70 kDa. Red - loading control, Anti-GAPDH antibody [6C5] - Loading Control ab8245 observed at 37 kDa.ab133602 Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] was shown to specifically react with Placental alkaline phosphatase (PLAP) in wild-type HeLa cells. Loss of signal was observed when knockout cell line Human ALPP (PLAP) knockout HeLa cell line ab261763 (knockout cell lysate Human ALPP (PLAP) knockout HeLa cell lysate ab256836) was used. Wild-type and Placental alkaline phosphatase (PLAP) knockout samples were subjected to SDS-PAGE. ab133602 and Anti-GAPDH antibody [6C5] - Loading Control (Anti-GAPDH antibody [6C5] - Loading Control ab8245) were incubated overnight at 4°C at 1 in 1000 dilution and 1 in 20000 dilution respectively. Blots were developed with Goat anti-Rabbit IgG H&L (IRDye® 800CW) preadsorbed (Goat anti-Rabbit IgG H&L (IRDye® 800CW) preadsorbed ab216773) and Goat anti-Mouse IgG H&L (IRDye® 680RD) preadsorbed (Goat anti-Mouse IgG H&L (IRDye® 680RD) preadsorbed ab216776) secondary antibodies at 1 in 10000 dilution for 1 hour at room temperature before imaging.
All lanes: Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602) at 1/1000 dilution
Lane 1: Wild-type HeLa cell lysate at 20 µg
Lane 2: ALPP knockout HeLa cell lysate at 20 µg
Lane 3: Human placenta tissue lysate at 20 µg
Lane 4: Human heart tissue lysate at 20 µg
Performed under reducing conditions.
Predicted band size: 58 kDa
Observed band size: 70 kDa
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img119300.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
Immunohistochemical analysis of paraffin-embedded Human placenta tissue labelling Placental alkaline phosphatase (PLAP) with ab133602 at 1/250.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--western-blot-img125680.jpg "Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
All lanes: Western blot - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602) at 1/10000 dilution
Lane 1: Human placenta tissue lysate
Lane 2: Human seminoma tissue lysate
Lane 3: HeLa cell lysate at 10 µg
SecondaryAll lanes: HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 58 kDa
Observed band size: 70 kDa
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img71515.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
ab133602 showing positive staining in Normal placenta tissue.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img127061.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
Immunohistochemical analysis of paraffin-embedded Human dysgerminoma tissue labelling Placental alkaline phosphatase (PLAP) with ab133602 at 1/250.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img121857.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
ab133602 showing negative staining in Normal brain tissue.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img93446.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
ab133602 showing negative staining in Normal liver tissue.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img59722.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
ab133602 showing positive staining in Seminoma tissue.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img128854.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
ab133602 showing negative staining in Normal colon tissue.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img135456.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
ab133602 showing negative staining in Normal tonsil tissue.
Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
![OI-RD Scanning - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--oi-rd-scanning-img152744.jpg "OI-RD Scanning - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
OI-RD Scanning - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)
We have systematically measured KD (the equilibrium dissociation constant between the antibody and its antigen), of more than 840 recombinant antibodies to assess not only their individual KD values but also to see the average affinity of antibody.
Based on the comparison with published literature values for mouse monoclonal antibodies, Recombinant antibodies appear to be on average 1-2 order of magnitude higher affinity.
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img127061.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img121857.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img93446.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img59722.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img128854.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img135456.jpg/_jcr_content/renditions/webp-475.webp "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
![OI-RD Scanning - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602), expandable thumbnail](https://content.abcam.com/products/images/placental-alkaline-phosphatase-plap-antibody-epr6141-ab133602--oi-rd-scanning-img152744.jpg/_jcr_content/renditions/webp-475.webp "OI-RD Scanning - Anti-Placental alkaline phosphatase (PLAP) antibody [EPR6141] (ab133602)")
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com