Anti-Plasma Kallikrein 1B antibody
5
(6 Reviews)
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(4 Publications)
Rabbit Polyclonal Plasma Kallikrein 1B antibody. Suitable for ELISA, WB, IHC-P and reacts with Mouse, Human samples. Cited in 4 publications. Immunogen corresponding to Synthetic Peptide within Human KLKB1.
View Alternative Names
KLK3, KLKB1, Plasma kallikrein, Fletcher factor, Kininogenin, Plasma prekallikrein, PKK
Reactivity data
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Appropriate long-term storage conditions
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Supplementary information
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Biological function summary
Plasma Kallikrein 1B plays significant roles in the kinin-kallikrein system. Within this system it cleaves high-molecular-weight kininogen to release bradykinin a potent vasodilator. This enzyme is not part of a larger protein complex but operates independently to modulate various physiological responses. Plasma kallikrein's activity influences processes like pain vasodilation and inflammation making it important in homeostasis and acute-phase responses.
Pathways
Plasma Kallikrein 1B participates actively in the kallikrein-kinin and the contact activation pathways. In the kallikrein-kinin system it works alongside high-molecular-weight kininogen and factor XII which plays an important role in the intrinsic pathway of coagulation. Plasma kallikrein's enzymatic activities lead to the production of bradykinin and other peptides impacting blood pressure and inflammatory processes.
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Target data
Publications (4)
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Zoological research 45:1001-1012 PubMed39147715
2024
Applications
Unspecified application
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Unspecified reactive species
Frontiers in pharmacology 14:1287487 PubMed38178859
2024
Applications
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Unspecified reactive species
Science advances 7: PubMed33523981
2021
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Brain : a journal of neurology 143:1780-1797 PubMed32428221
2020
Applications
Unspecified application
Species
Unspecified reactive species
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