Goat Polyclonal Poliovirus (type 1-3) antibody. Suitable for ICC/IF and reacts with Enterovirus C samples. Cited in 3 publications. Immunogen corresponding to Virus preparation containing Poliovirus (type 1-3) protein.
IgG
Goat
pH: 7.2
Preservative: 0.1% Sodium azide
Constituents: PBS
Liquid
Polyclonal
ICC/IF | |
---|---|
Enterovirus C | Expected |
Species | Dilution info | Notes |
---|---|---|
Species Enterovirus C | Dilution info Use at an assay dependent concentration. | Notes - |
Goat Polyclonal Poliovirus (type 1-3) antibody. Suitable for ICC/IF and reacts with Enterovirus C samples. Cited in 3 publications. Immunogen corresponding to Virus preparation containing Poliovirus (type 1-3) protein.
IgG
Goat
pH: 7.2
Preservative: 0.1% Sodium azide
Constituents: PBS
Liquid
Polyclonal
Proprietary technique
Poliovirus Types 1, 2 & 3
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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This supplementary information is collated from multiple sources and compiled automatically.
Poliovirus (type 1-3) also known as human poliovirus is a member of the Enterovirus genus. It is a small non-enveloped virus with an icosahedral capsid. The most common types are 1 2 and 3 each with slight variations in their viral capsid proteins. Poliovirus has an approximate molecular mass of 8.4 kilodaltons for its viral protein 1. It primarily expresses in human cells specifically targeting the gastrointestinal tract where initial replication occurs.
Polio is a highly contagious viral pathogen responsible for initiating poliomyelitis. The virus targets motor neurons within the spinal cord and the brainstem leading to paralysis. Poliovirus achieves its biological role by interacting with the host cell receptor known as CD155 and not part of a protein complex but acts as a singular threat to CNS tissues.
Poliovirus infection involves significant genetic replication and translation processes. This takes place through the cellular machinery of the host particularly using the internal ribosome entry site (IRES) mechanism instead of traditional cap-dependent translation. Related proteins in these pathways include eukaryotic translation initiation factors (eIFs) which are co-opted by the virus to facilitate its replication.
Poliovirus causes poliomyelitis an acute viral condition which can lead to significant neurological impairment including paralysis. The virus spreads through fecal-oral transmission and the potential for neurological damage connects it to proteins like neuron-specific enolase (NSE) commonly released as a result of neuronal injury. Additionally due to its highly infectious nature poliovirus has been studied extensively as part of efforts in eradication programs directly linking it to public health efforts in preventing outbreaks.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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