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Goat Polyclonal Poliovirus (type 1-3) antibody. Suitable for ICC/IF and reacts with Enterovirus C samples. Cited in 3 publications. Immunogen corresponding to Virus preparation containing Poliovirus (type 1-3) protein.

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Publications

Key facts

Isotype

IgG

Host species

Goat

Storage buffer

pH: 7.2
Preservative: 0.1% Sodium azide
Constituents: PBS

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Virus preparation containing Poliovirus (type 1-3) protein. The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
ICC/IF
Enterovirus C
Expected

Expected
Expected

Species

Enterovirus C

Dilution info

Use at an assay dependent concentration.

Notes

-

Recommended products

Goat Polyclonal Poliovirus (type 1-3) antibody. Suitable for ICC/IF and reacts with Enterovirus C samples. Cited in 3 publications. Immunogen corresponding to Virus preparation containing Poliovirus (type 1-3) protein.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Virus preparation containing Poliovirus (type 1-3) protein. The exact immunogen used to generate this antibody is proprietary information.
Purification technique

Proprietary technique

Specificity

Poliovirus Types 1, 2 & 3

Concentration
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Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

Poliovirus (type 1-3) also known as human poliovirus is a member of the Enterovirus genus. It is a small non-enveloped virus with an icosahedral capsid. The most common types are 1 2 and 3 each with slight variations in their viral capsid proteins. Poliovirus has an approximate molecular mass of 8.4 kilodaltons for its viral protein 1. It primarily expresses in human cells specifically targeting the gastrointestinal tract where initial replication occurs.

Biological function summary

Polio is a highly contagious viral pathogen responsible for initiating poliomyelitis. The virus targets motor neurons within the spinal cord and the brainstem leading to paralysis. Poliovirus achieves its biological role by interacting with the host cell receptor known as CD155 and not part of a protein complex but acts as a singular threat to CNS tissues.

Pathways

Poliovirus infection involves significant genetic replication and translation processes. This takes place through the cellular machinery of the host particularly using the internal ribosome entry site (IRES) mechanism instead of traditional cap-dependent translation. Related proteins in these pathways include eukaryotic translation initiation factors (eIFs) which are co-opted by the virus to facilitate its replication.

Associated diseases and disorders

Poliovirus causes poliomyelitis an acute viral condition which can lead to significant neurological impairment including paralysis. The virus spreads through fecal-oral transmission and the potential for neurological damage connects it to proteins like neuron-specific enolase (NSE) commonly released as a result of neuronal injury. Additionally due to its highly infectious nature poliovirus has been studied extensively as part of efforts in eradication programs directly linking it to public health efforts in preventing outbreaks.

Product promise

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