AB93102
Anti-POLRMT antibody
1
(1 Review)
|
(2 Publications)
Rabbit Polyclonal POLRMT antibody. Suitable for ChIP, ELISA, WB and reacts with Recombinant fragment samples. Cited in 2 publications.
View Alternative Names
MtRPOL, POLRMT
Reactivity data
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Properties and storage information
Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Purity >90%
Storage buffer
pH: 7.2 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
Product protocols
For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data
DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates (PubMed : 21278163, PubMed : 33602924). Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA (PubMed : 29149603). In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping of the DNA non-template strand (PubMed : 29149603). Has DNA primase activity (PubMed : 18685103, PubMed : 33602924). Catalyzes the synthesis of short RNA primers that are necessary for the initiation of lagging-strand DNA synthesis from the origin of light-strand DNA replication (OriL) (PubMed : 18685103, PubMed : 33602924).
Publications (2)
Recent publications for all applications. Explore the full list and refine your search
Cell 167:722-738.e23 PubMed27768893
2016
MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.
Applications
Unspecified application
Species
Unspecified reactive species
Aindrila Chatterjee,Janine Seyfferth,Jacopo Lucci,Ralf Gilsbach,Sebastian Preissl,Lena Böttinger,Christoph U Mårtensson,Amol Panhale,Thomas Stehle,Oliver Kretz,Abdullah H Sahyoun,Sergiy Avilov,Stefan Eimer,Lutz Hein,Nikolaus Pfanner,Thomas Becker,Asifa Akhtar
PloS one 6:e22583 PubMed21799907
2011
Transcription of muscle actin genes by a nuclear form of mitochondrial RNA polymerase.
Applications
ChIP
Species
Human
Yu-Ling Lee,Chun-Hui Chiao,Ming-Ta Hsu
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