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AB198280

Anti-PPAP2A antibody

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(2 Publications)

Rabbit Polyclonal PPAP2A antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human PLPP1.

View Alternative Names

LPP1, PPAP2A, PLPP1, Phospholipid phosphatase 1, Lipid phosphate phosphohydrolase 1, PAP2-alpha, Phosphatidate phosphohydrolase type 2a, Phosphatidic acid phosphatase 2a, PAP-2a, PAP2a

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPAP2A antibody (AB198280)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPAP2A antibody (AB198280)

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue labeling PPAP2A with ab198280 at 1/40 dilution.

Western blot - Anti-PPAP2A antibody (AB198280)
  • WB

Supplier Data

Western blot - Anti-PPAP2A antibody (AB198280)

10% SDS-PAGE

All lanes:

Western blot - Anti-PPAP2A antibody (ab198280) at 1/650 dilution

All lanes:

Human liver cancer tissue lysate at 30 µg

Predicted band size: 32 kDa

false

Exposure time: 1s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human PLPP1. The exact immunogen used to generate this antibody is proprietary information.

O14494

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/25 - 1/100", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Magnesium-independent phospholipid phosphatase of the plasma membrane that catalyzes the dephosphorylation of a variety of glycerolipid and sphingolipid phosphate esters including phosphatidate/PA, lysophosphatidate/LPA, diacylglycerol pyrophosphate/DGPP, sphingosine 1-phosphate/S1P and ceramide 1-phosphate/C1P (PubMed : 10962286, PubMed : 17379599, PubMed : 9305923, PubMed : 9607309, PubMed : 9705349). Also acts on N-oleoyl ethanolamine phosphate/N-(9Z-octadecenoyl)-ethanolamine phosphate, a potential physiological compound (PubMed : 9607309). Through its extracellular phosphatase activity allows both the hydrolysis and the cellular uptake of these bioactive lipid mediators from the milieu, regulating signal transduction in different cellular processes (PubMed : 10962286, PubMed : 12909631, PubMed : 15461590, PubMed : 17379599). It is for instance essential for the extracellular hydrolysis of S1P and subsequent conversion into intracellular S1P (PubMed : 17379599). Involved in the regulation of inflammation, platelets activation, cell proliferation and migration among other processes (PubMed : 12909631, PubMed : 15461590). May also have an intracellular activity to regulate phospholipid-mediated signaling pathways (By similarity).
See full target information PLPP1
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 9:12989 PubMed31506451

2019

Stimulated phospholipid synthesis is key for hepatitis B virus replications.

Applications

Unspecified application

Species

Unspecified reactive species

Qingxia Huang,Hehua Lei,Laifeng Ding,Yulan Wang

BBA clinical 6:76-81 PubMed27453821

2016

Lipid profile of platelets and platelet-derived microparticles in ovarian cancer.

Applications

WB

Species

Human

Qianghua Hu,Miao Wang,Min Soon Cho,Chunyan Wang,Alpa M Nick,Perumal Thiagarajan,Fleur M Aung,Xianlin Han,Anil K Sood,Vahid Afshar-Kharghan
View all publications
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Product promise

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