Rabbit Polyclonal PPAR alpha antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 25 publications.
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- Journal of dairy science 107:3127-31392023Inositol-requiring enzyme 1α and c-Jun N-terminal kinase axis activation contributes to intracellular lipid accumulation in calf hepatocytes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWenwen Gao,Yanxi Wang,Siyu Liu,Guojin Li,Qi Shao,Cai Zhang,Liguang Cao,Kai Liu,Wenrui Gao,Zifeng Yang,Yifei Dong,Xiliang Du,Lin Lei,Guowen Liu,Xinwei LiPubMed 37939835
- Nature communications 14:54512023Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJing Zhong,Xiaofang He,Xinxin Gao,Qiaohong Liu,Yu Zhao,Ying Hong,Weize Zhu,Juan Yan,Yifan Li,Yan Li,Ningning Zheng,Yiyang Bao,Hao Wang,Junli Ma,Wenjin Huang,Zekun Liu,Yuanzhi Lyu,Xisong Ke,Wei Jia,Cen Xie,Yiyang Hu,Lili Sheng,Houkai LiPubMed 37673856
- Frontiers in nutrition 9:10697972022Preparation of microgel co-loaded with nuciferine and epigallocatechin-3-gallate for the regulation of lipid metabolism.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShengnan Zhu,Weijia Xu,Jun Liu,Feng Guan,Aichun Xu,Jin Zhao,Jian GePubMed 36579075
- Nutrients 14:2022Ramulus Mori (Sangzhi) Alkaloids Ameliorate Obesity-Linked Adipose Tissue Metabolism and Inflammation in Mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQian-Wen Sun,Chun-Fang Lian,Yan-Min Chen,Jun Ye,Wei Chen,Yue Gao,Hong-Liang Wang,Li-Li Gao,Yu-Ling Liu,Yan-Fang YangPubMed 36501080
- Frontiers in immunology 13:10054302022The protective role of caffeic acid on bovine mammary epithelial cells and the inhibition of growth and biofilm formation of Gram-negative bacteria isolated from clinical mastitis milk.Applications:Unspecified applicationReactive species:Unspecified reactive speciesTianle Xu,Hao Zhu,Run Liu,Xinyue Wu,Guangjun Chang,Yi Yang,Zhangping YangPubMed 36341408
- Frontiers in pharmacology 13:9155352022Systematic characterization of Puerariae Flos metabolites and assessment of its protective mechanisms against alcoholic liver injury in a rat model.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJialin Qu,Qiuyue Chen,Tianfu Wei,Ning Dou,Dong Shang,Dan YuanPubMed 36110520
- Frontiers in pharmacology 13:9155922022Bailing capsule () ameliorates renal triglyceride accumulation through the PPARα pathway in diabetic rats.Applications:Unspecified applicationReactive species:Unspecified reactive speciesQian Zhang,Xinhua Xiao,Ming Li,Miao Yu,Fan PingPubMed 36091833
- Journal of applied oral science : revista FOB 30:e202200762022In vitro and in vivo study of the pathogenic role of PPARα in experimental periodontitis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYing Chen,Zheqing Jiang,Ana Keohane,Yang HuPubMed 35830121
- Frontiers in bioengineering and biotechnology 10:8585582022LncRNA MALAT1 Promotes PPARα/CD36-Mediated Hepatic Lipogenesis in Nonalcoholic Fatty Liver Disease by Modulating miR-206/ARNT Axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJuan Xiang,Yuan-Yuan Deng,Hui-Xia Liu,Ying PuPubMed 35769097
- Antioxidants (Basel, Switzerland) 11:2022(Sangzhi) Alkaloids Alleviate High-Fat Diet-Induced Obesity and Nonalcoholic Fatty Liver Disease in Mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYan-Min Chen,Chun-Fang Lian,Qian-Wen Sun,Ting-Ting Wang,Yuan-Yuan Liu,Jun Ye,Li-Li Gao,Yan-Fang Yang,Shuai-Nan Liu,Zhu-Fang Shen,Yu-Ling LiuPubMed 35624769
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA- Form
Liquid
- Clonality
Polyclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| WB | |
|---|---|
| Human | Tested |
| Mouse | Tested |
| Rat | Predicted |
| Cow | Predicted |
| Dog | Predicted |
| Gorilla | Predicted |
| Macaque monkey | Predicted |
| Orangutan | Predicted |
| Rabbit | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1 µg/mL | Notes - |
Species Human | Dilution info 1 µg/mL | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat, Rabbit, Cow, Dog, Macaque monkey, Gorilla, Orangutan | Dilution info - | Notes - |
Associated Products
Select an associated product type
7 products for Alternative Product
Target data
Function
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as a transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Alternative names
NR1C1, PPAR, NR1C1, PPARA, PPAR, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1
Recommended products
Rabbit Polyclonal PPAR alpha antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 25 publications.
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: 98.98% PBS, 1% BSA- Form
Liquid
- Clonality
Polyclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Purification technique
Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-PPAR alpha antibody (ab126285)
All lanes: Western blot - Anti-PPAR alpha antibody (ab126285) at 1 µg/mL
Lane 1: HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate at 10 µg
Lane 2: HEK293 (Human embryonic kidney cell line) Whole Cell Lysate at 10 µg
Lane 3: Jurkat (Human T cell lymphoblast-like cell line) Whole Cell Lysate at 10 µg
Lane 4: NIH 3T3 (Mouse embryonic fibroblast cell line) Whole Cell Lysate at 10 µg
SecondaryAll lanes: Western blot - Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (Goat Anti-Rabbit IgG H&L (HRP) preadsorbed ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 52 kDa
Observed band size: 37 kDa, 50 kDa, 52 kDa
Exposure time: 1min
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