Rabbit Polyclonal PPAR alpha antibody. Suitable for WB and reacts with Rat samples. Cited in 13 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PPARA.
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- Cells 12:2023RXR Agonists Enhance Lenalidomide Anti-Myeloma Activity and T Cell Functions while Retaining Glucose-Lowering Effect.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJian Wu,Xiaobei Wang,Min Zhang,Parker Mathews,Yubin KangPubMed 37566072
- Molecular pharmacology 103:145-1572022Valproic Acid-Induced Upregulation of Multidrug Efflux Transporter ABCG2/BCRP via PPAR-Dependent Mechanism in Human Brain Endothelial Cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSamiksha Kukal,Shivangi Bora,Neha Kanojia,Pooja Singh,Priyanka Rani Paul,Chitra Rawat,Shakti Sagar,Naveen Kumar Bhatraju,Gurpreet Kaur Grewal,Anju Singh,Shrikant Kukreti,Kapaettu Satyamoorthy,Ritushree KukretiPubMed 36414374
- Antioxidants (Basel, Switzerland) 11:2022Therapeutic Effect of Curcumin on 5/6Nx Hypertriglyceridemia: Association with the Improvement of Renal Mitochondrial β-Oxidation and Lipid Metabolism in Kidney and Liver.Applications:Unspecified applicationReactive species:Unspecified reactive speciesZeltzin Alejandra Ceja-Galicia,Fernando Enrique García-Arroyo,Omar Emiliano Aparicio-Trejo,Mohammed El-Hafidi,Guillermo Gonzaga-Sánchez,Juan Carlos León-Contreras,Rogelio Hernández-Pando,Martha Guevara-Cruz,Armando R Tovar,Pedro Rojas-Morales,Ana Karina Aranda-Rivera,Laura Gabriela Sánchez-Lozada,Edilia Tapia,José Pedraza-ChaverriPubMed 36358567
- Haematologica 107:2589-26002022Interplay between hypertriglyceridemia and acute promyelocytic leukemia mediated by the cooperation of peroxisome proliferator-activated receptor-α with the PML/RAR α fusion protein on super-enhancers.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShishuang Wu,Shufen Li,Peng Jin,Yi Zhang,Li Chen,Wen Jin,Junmin Li,Kankan WangPubMed 35546300
- Cancers 14:2022Mechanistic Studies and a Retrospective Cohort Study: The Interaction between PPAR Agonists and Immunomodulatory Agents in Multiple Myeloma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJian Wu,Emily Chu,Barry Paul,Yubin KangPubMed 36358696
- Diabetes research and clinical practice 191:1100662022The pivotal role of miRNA-21 in myocardial metabolic flexibility in response to short- and long-term high glucose treatment: Evidence in human cardiomyocyte cell line.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLucia Scisciola,Rosaria Benedetti,Ugo Chianese,Rosaria Anna Fontanella,Nunzio Del Gaudio,Raffaele Marfella, Surina,Lucia Altucci,Michelangela Barbieri,Giuseppe PaolissoPubMed 36058441
- Cancer letters 545:2158322022PPAR agonists attenuate lenalidomide's anti-myeloma activity in vitro and in vivo.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYonggang Sha,Jian Wu,Barry Paul,Yue Zhao,Parker Mathews,Zhiguo Li,John Norris,Endi Wang,Donald P McDonnell,Yubin KangPubMed 35872263
- Frontiers in pharmacology 13:8933362022Exploring Ganweikang Tablet as a Candidate Drug for NAFLD Through Network Pharmacology Analysis and Experimental Validation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChuanrui Ma,Xinyu Wang,Jing Zhang,Yun Zhao,Yunqing Hua,Chao Zhang,Guobin Zheng,Guangyan Yang,Jianli Guan,Huahuan Li,Meng Li,Lin Kang,Jiaqing Xiang,Guanwei Fan,Shu YangPubMed 35774609
- The Journal of clinical investigation 131:2021Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSumita Mishra,Nandhini Sadagopan,Brittany Dunkerly-Eyring,Susana Rodriguez,Dylan C Sarver,Ryan P Ceddia,Sean A Murphy,Hildur Knutsdottir,Vivek P Jani,Deepthi Ashok,Christian U Oeing,Brian O'Rourke,Jon A Gangoiti,Dorothy D Sears,G William Wong,Sheila Collins,David A KassPubMed 34618683
- Metabolic brain disease 36:1779-17902021Icariin enhance mild hypothermia-induced neuroprotection via inhibiting the activation of NF-κB in experimental ischemic stroke.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMingming Dai,Bin Chen,Xiaozhi Wang,Chang Gao,Hang YuPubMed 33978900
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human PPARA. The exact immunogen used to generate this antibody is proprietary information. Database link Q07869
Reactivity data
Select an application| WB | |
|---|---|
| Human | Predicted |
| Rat | Tested |
| Dog | Predicted |
| Pig | Predicted |
| Rhesus monkey | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 1/500 - 1/3000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Dog, Human, Pig, Rhesus monkey | Dilution info - | Notes - |
Associated Products
Select an associated product type
3 products for Alternative Product
Target data
Function
Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as a transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Alternative names
NR1C1, PPAR, PPARA, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1
Recommended products
Rabbit Polyclonal PPAR alpha antibody. Suitable for WB and reacts with Rat samples. Cited in 13 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PPARA.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7
Preservative: 0.025% Proclin 300
Constituents: 79% PBS, 20% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human PPARA. The exact immunogen used to generate this antibody is proprietary information. Database link Q07869
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-PPAR alpha antibody (ab227074)
7.5% SDS-PAGE gel.
All lanes: Western blot - Anti-PPAR alpha antibody (ab227074) at 1/1000 dilution
All lanes: Rat primary hepatocyte lysate at 30 µg
SecondaryAll lanes: HRP-conjugated anti-rabbit IgG
Predicted band size: 52 kDa
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