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AB23673

Anti-PPAR delta antibody

4

(11 Reviews)

|

(55 Publications)

Rabbit Polyclonal PPAR delta antibody. Suitable for WB, ICC/IF and reacts with Mouse, Human samples. Cited in 55 publications. Immunogen corresponding to Synthetic Peptide within Human PPARD aa 1-100.

View Alternative Names

NR1C2, PPARB, PPARD, Peroxisome proliferator-activated receptor delta, PPAR-delta, NUCI, Nuclear hormone receptor 1, Nuclear receptor subfamily 1 group C member 2, Peroxisome proliferator-activated receptor beta, NUC1, PPAR-beta

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-PPAR delta antibody (AB23673)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-PPAR delta antibody (AB23673)

Immunofluorescent staining of HT-29 cells (ab3952) (nuclear staining) using ab23673.

Western blot - Anti-PPAR delta antibody (AB23673)
  • WB

Unknown

Western blot - Anti-PPAR delta antibody (AB23673)

ab23673 recognises PPAR delta at 50kDa from human samples. An additional smaller size of PPAR delta (~40kDa) is also detected in certain murine tissues.

All lanes:

Western blot - Anti-PPAR delta antibody (ab23673)

Lane 1:

Human cerebral cortex (30ug)

Lane 2:

Murine liver (30ug)

Predicted band size: 50 kDa

false

Western blot - Anti-PPAR delta antibody (AB23673)
  • WB

AbReview38239****

Western blot - Anti-PPAR delta antibody (AB23673)

All lanes:

Western blot - Anti-PPAR delta antibody (ab23673) at 1/1000 dilution

All lanes:

Rat brain tissue lysate at 100 µg

Secondary

All lanes:

HRP-conjugate Goat anti-rabbit IgG polyclonal at 1/2000 dilution

Predicted band size: 50 kDa

Observed band size: 54 kDa

true

Exposure time: 30s

This image is courtesy of an anonymous Abreview

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Human PPARD aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q03181

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "2 µg/mL", "WB-species-notes": "<p>Nuclear extraction may be required in some samples. Detects a band of approximately 50 kDa in human samples, and an additional smaller size of PPAR delta is detected in some murine samples at approximately 40 kDa.</p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "4 µg/mL", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "2 µg/mL", "WB-species-notes": "<p>Nuclear extraction may be required in some samples. Detects a band of approximately 50 kDa in human samples, and an additional smaller size of PPAR delta is detected in some murine samples at approximately 40 kDa.</p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues (PubMed : 35675826). Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
See full target information PPARD

Publications (55)

Recent publications for all applications. Explore the full list and refine your search

JCI insight 10: PubMed40996961

2025

CDK12 regulates cellular metabolism to promote glioblastoma growth.

Applications

Unspecified application

Species

Unspecified reactive species

Jeong-Yeon Mun,Chang Shu,Qiuqiang Gao,Zhe Zhu,Hasan O Akman,Mike-Andrew Westhoff,Georg Karpel-Massler,Markus D Siegelin

Theranostics 15:8985-9000 PubMed40963917

2025

Extracellular vehicles-mediated Twsit1 transferred from tumor cells to brain induces depressive-like behaviors via neuronal morphogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

Ruo-Si Zou,Jin-Gang He,Yang Zhao,Bing Zhou,Si-Long Deng,Jian-Guo Chen,Fang Wang

Biomedicines 12: PubMed39595188

2024

p75NTR Modulation Reduces Oxidative Stress and the Expression of Pro-Inflammatory Mediators in a Cell Model of Rett Syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Michela Varone,Giuseppe Scavo,Mayra Colardo,Noemi Martella,Daniele Pensabene,Emanuele Bisesto,Andrea Del Busso,Marco Segatto

Molecules (Basel, Switzerland) 29: PubMed39519830

2024

Selective PPARδ Agonist GW501516 Protects Against LPS-Induced Macrophage Inflammation and Acute Liver Failure in Mice via Suppressing Inflammatory Mediators.

Applications

Unspecified application

Species

Unspecified reactive species

Hyun-Joung Lim,Hyun Jeong Kwak

Research (Washington, D.C.) 7:0400 PubMed38939042

2024

Brain Short-Chain Fatty Acids Induce ACSS2 to Ameliorate Depressive-Like Behavior via PPARγ-TPH2 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Nuo Chen,Xinyi Xu,Yaxin Guo,Ming Zhao,Yubin Li,Tian Zhou,Xinyue Zhang,Jie Gao,Faliang Zhu,Chun Guo,Yongyu Shi,Qun Wang,Wenxian Wu,Lining Zhang,Yan Li

Neural regeneration research 21:377-391 PubMed38934394

2024

Chitosan alleviates symptoms of Parkinson's disease by reducing acetate levels, which decreases inflammation and promotes repair of the intestinal barrier and blood-brain barrier.

Applications

Unspecified application

Species

Unspecified reactive species

Yinying Wang,Rongsha Chen,Guolin Shi,Xinwei Huang,Ke Li,Ruohua Wang,Xia Cao,Zhongshan Yang,Ninghui Zhao,Jinyuan Yan

Frontiers in pharmacology 15:1336282 PubMed38576477

2024

PPARδ agonist protects against osteoarthritis by activating AKT/mTOR signaling pathway-mediated autophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Guantong Sun,Xiaodong Li,Pengcheng Liu,Yao Wang,Cheng Yang,Shuhong Zhang,Lei Wang,Xiaoqing Wang

BMC cancer 23:1042 PubMed37904094

2023

Low-dose adropin stimulates inflammasome activation of macrophage via mitochondrial ROS involved in colorectal cancer progression.

Applications

Unspecified application

Species

Unspecified reactive species

Linghui Jia,Liting Liao,Yongshuai Jiang,Xiangyu Hu,Guotao Lu,Weiming Xiao,Weijuan Gong,Xiaoqin Jia

International journal of molecular sciences 24: PubMed37511155

2023

Smad3 Mediates Diabetic Dyslipidemia and Fatty Liver in db/db Mice by Targeting PPARδ.

Applications

Unspecified application

Species

Unspecified reactive species

Huijun He,Yu Zhong,Honglian Wang,Patrick Ming-Kuen Tang,Vivian Weiwen Xue,Xiaocui Chen,Jiaoyi Chen,Xiaoru Huang,Cheng Wang,Huiyao Lan

Nature communications 13:6723 PubMed36344546

2022

CD1d-dependent rewiring of lipid metabolism in macrophages regulates innate immune responses.

Applications

Unspecified application

Species

Unspecified reactive species

Phillip M Brailey,Lauren Evans,Juan Carlos López-Rodríguez,Anthony Sinadinos,Victoria Tyrrel,Gavin Kelly,Valerie O'Donnell,Peter Ghazal,Susan John,Patricia Barral
View all publications

Product promise

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