AB41928

Anti-PPAR gamma antibody [A3409A]

Name: Anti-PPAR gamma antibody [A3409A] (ab41928) | Abcam
Brand: Abcam Limited
SKU: AB41928
Price: 435 USD
Availability: InStock
Rating: 5 (2 reviews)

(2 Reviews)

(66 Publications)

Mouse Monoclonal PPAR gamma antibody. Suitable for IP, WB, IHC-P and reacts with Recombinant fragment - Human, Human, Mouse, Rat samples. Cited in 66 publications. Immunogen corresponding to Recombinant Fragment Protein within Human PPARG aa 1-150.

View Alternative Names

NR1C3, PPARG, Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3

3 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPAR gamma antibody [A3409A] (AB41928)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPAR gamma antibody [A3409A] (AB41928)

ab41928 staining PPAR gamma in rat adipose cells (10 ug/mL) by immunohistochemistry, formalin-fixed paraffin embedded sections.

This image was generated using the ascites version of the product.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPAR gamma antibody [A3409A] (AB41928)

ab41928 staining PPAR gamma in rat placenta (10 ug/mL) by immunohistochemistry, formalin-fixed paraffin embedded sections.

This image was generated using the ascites version of the product.

Lab

Immunoprecipitation - Anti-PPAR gamma antibody [A3409A] (AB41928)

Lane 1 : FLAG-M2
Lane 2 : ab41928
Lane 3 : ab41928
Lane 4 : Control IgG

Immunoprecipitation analysis using Fluorescence labeled PPAR gamma generated in vitro translation. Anti-PPAR gamma antibody (ab41928) is diluted with translation production and mixed with protein G Sepharose beads. It is then rotated at 4°C for 1 hour and precipitates are eluted with addition of SDS loading buffer. Samples are incubated for 10minutes at 70°C and analyzed with Fluorescence imager.

This image was generated using the ascites version of the product.

All lanes:

Immunoprecipitation - Anti-PPAR gamma antibody [A3409A] (ab41928)

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Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

A3409A

Isotype

IgG2a

Carrier free

Reacts with

Mouse, Rat, Human

Applications

IP, WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human PPARG aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

P37231

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "A nuclear extraction is recommended.", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "Perform antigen retrieval by autoclave to preserve reproducibility. Sections should be fixed with formalin for no longer than 48 hours." }, "Mouse": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "A nuclear extraction is recommended.", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "Perform antigen retrieval by autoclave to preserve reproducibility. Sections should be fixed with formalin for no longer than 48 hours." }, "Recombinant fragment - Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Product details

This product was changed from ascites to tissue culture supernatant on 3^rd April 2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

pH: 7 Preservative: 0.1% Sodium azide

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of BMAL1 in the blood vessels (By similarity).. (Microbial infection) Upon treatment with M.tuberculosis or its lipoprotein LpqH, phosphorylation of MAPK p38 and IL-6 production are modulated, probably via this protein.

See full target information PPARG

Additional targets

PPARG

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Publications (66)

Recent publications for all applications. Explore the full list and refine your search

Food science & nutrition 13:e71009 PubMed40994455

2025

Screening Based on Structural and Biological Verification of Stachyose as a PPARγ-Modulating Ligand for the Treatment of Non-Alcoholic Fatty Liver Disease.

Applications

Unspecified application

Species

Unspecified reactive species

Binbo Fang,Mengyuan Li,Feng Jiang,Weisong Dong,Weizhi Zhang,Lifan Lin,Yongheng Bai,Jianjian Zheng

Frontiers in neurology 16:1642150 PubMed40860972

2025

Electroacupuncture enhances mesenchymal stem cell therapy via improved perfusion and inflammation modulation in peripheral nerve injury: an IVIM-MRI study in rats.

Applications

Unspecified application

Species

Unspecified reactive species

Junfeng Li,Qiuyi Chen,Jintong Pan,Fanqi Meng,Wensheng Huang,Yingying Liang,Xuewen Yu,Ruirui Qi,Peiyin Luo,Haodong Qin,Yueyao Chen,Xiaofeng Lin

Journal of nanobiotechnology 22:648 PubMed39438865

2024

Exosomal miR-1a-3p derived from glucocorticoid-stimulated M1 macrophages promotes the adipogenic differentiation of BMSCs in glucocorticoid-associated osteonecrosis of the femoral head by targeting Cebpz.

Applications

Unspecified application

Species

Unspecified reactive species

Ping Duan,Yong-Le Yu,Yan-Nan Cheng,Meng-Han Nie,Qing Yang,Liang-Hui Xia,Yan-Xiao Ji,Zhen-Yu Pan

Aging 16:9410-9436 PubMed38848145

2024

APOA5 alleviates reactive oxygen species to promote oxaliplatin resistance in PIK3CA-mutated colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Yu-Lin Liu,Zhuo Xiang,Bo-Ya Zhang,Yu-Wei Zou,Gui-Lai Chen,Li Yin,Yan-Long Shi,Li-Li Xu,Jingwang Bi,Qiang Wang

International journal of nanomedicine 19:1683-1697 PubMed38445226

2024

Hydrophilic/Hydrophobic Janus Nanofibers Containing Compound K for Cartilage Regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Hyun Ho Shin,Junyoung Park,Yeo-Jin Kim,Donghyeon Kim,Eun-Jung Jin,Ji Hyun Ryu

Journal of orthopaedic surgery and research 19:127 PubMed38326818

2024

Icariin promotes bone marrow mesenchymal stem cells osteogenic differentiation via the mTOR/autophagy pathway to improve ketogenic diet-associated osteoporosis.

Applications

Unspecified application

Species

Unspecified reactive species

Wei Liu,Shouyu Xiang,Yingcong Wu,Dinghao Zhang,Chuhai Xie,Hailan Hu,Qi Liu

International journal of molecular sciences 25: PubMed38203362

2024

The Effect of an Innovative Combination of Bergamot Polyphenolic Fraction and L. Extract on Weight Gain Reduction and Fat Browning in Obese Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Saverio Nucera,Federica Scarano,Roberta Macrì,Rocco Mollace,Micaela Gliozzi,Cristina Carresi,Stefano Ruga,Maria Serra,Annamaria Tavernese,Rosamaria Caminiti,Annarita Coppoletta,Antonio Cardamone,Tiziana Montalcini,Arturo Pujia,Ernesto Palma,Carolina Muscoli,Francesco Barillà,Vincenzo Musolino,Vincenzo Mollace

Frontiers in endocrinology 14:1212291 PubMed37780625

2023

PM induced liver lipid metabolic disorders in C57BL/6J mice.

Applications

Unspecified application

Species

Unspecified reactive species

Chenxiao Zhang,Tengfei Ma,Chang Liu,Ding Ma,Jian Wang,Meng Liu,Jinjun Ran,Xueting Wang,Xiaobei Deng

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 37:e23031 PubMed37342917

2023

LSD1 interacting with HSP90 promotes skin wound healing by inducing metabolic reprogramming of hair follicle stem cells through the c-MYC/LDHA axis.

Applications

Unspecified application

Species

Unspecified reactive species

Shuiqi Li,Jie Yu,Jiangan Zhang,Xiaohong Li,Jianbin Yu

iScience 25:105135 PubMed36185359

2022

Deficiency of peroxisomal NUDT7 stimulates lipogenesis in hepatocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Jinsoo Song,In-Jeoung Baek,Sujeong Park,Jinjoo Oh,Deokha Kim,Kyung Song,Mi Kyung Kim,Hye Won Lee,Byoung Kuk Jang,Eun-Jung Jin

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PPAR gamma antibody [A3409A]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPAR gamma antibody [A3409A] (AB41928)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PPAR gamma antibody [A3409A] (AB41928)

Immunoprecipitation - Anti-PPAR gamma antibody [A3409A] (AB41928)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Additional targets

Publications (66)

Complementary Products

Assay Kits

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise