AB272718

Anti-PPAR gamma antibody [EPR23297-111]

Name: Anti-PPAR gamma antibody [EPR23297-111] (ab272718) | Abcam
Brand: Abcam Limited
SKU: AB272718
Price: 610 USD
Availability: InStock
Rating: 2 (1 reviews)

RabMAb
Recombinant
What is this?

(1 Review)

(50 Publications)

Anti-PPAR gamma antibody [EPR23297-111] (ab272718) is a rabbit monoclonal antibody detecting PPAR gamma in ICC/IF. Suitable for Human, Mouse, Rat.

- Biophysical QC for unrivalled batch-batch consistency
- Over 20 publications

View Alternative Names

NR1C3, PPARG, Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3

1 Images

Immunocytochemistry/ Immunofluorescence - Anti-PPAR gamma antibody [EPR23297-111] (AB272718)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-PPAR gamma antibody [EPR23297-111] (AB272718)

Immunofluorescent analysis of 4% Paraformaldehyde-fixed, 0.1% TritonX-100 permeabilized 3T3-L1 (mouse embryonic fibroblast) cells labelling PPAR gamma with ab272718 at 1/100 (5.5 ug/ml) dilution (Green). Confocal image showing increased nuclear staining in differentiated 3T3-L1 cells (shown in green).

Nuclear DNA was labelled with DAPI (shown in blue). Secondary used was ab150081 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) preadsorbed at 1/1000 (2 ug/ml). ab195889 Anti-alpha Tubulin mouse monoclonal antibody - Microtubule Marker (Alexa Fluor® 594) was used to counterstain tubulin at 1/200 2.5ug/ml dilution (Magenta).

Image was taken with a confocal microscope (Leica-Microsystems, TCS SP8).

Carrier free

Anti-PPAR gamma antibody [EPR23297-111] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR23297-111

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

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Product details

What is this antibody validated in?
Anti-PPAR gamma antibody [EPR23297-111] (ab272718) is a rabbit recombinant monoclonal antibody and is validated for use in Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples.

Trusted by the scientific community
Anti-PPAR gamma [EPR23297-111] (ab272718) was first used in a scientific publication in 2020 and has been cited over 20 times in peer-reviewed journals.

Trial sizes available!
Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies.

Other related products
We have a range of other formats of antibody clone [EPR23297-111] also available for your convenience: ab272718, Carrier free - ab273502

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of BMAL1 in the blood vessels (By similarity).. (Microbial infection) Upon treatment with M.tuberculosis or its lipoprotein LpqH, phosphorylation of MAPK p38 and IL-6 production are modulated, probably via this protein.

See full target information PPARG

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Publications (50)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine reports 32: PubMed40999952

2025

HSPD1 regulates angiotensin II‑induced atrial fibrillation via the PPAR signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yimeng Zhou,Lianzhi Zhang,Shunping Zhou,Wenjia Zhang,Qunlin Gong,Nan Xu,Jiahong Wang,Zhong Zhang,Nannan Chen

Biomolecules 15: PubMed40867523

2025

Artesunate Ameliorates SLE Atherosclerosis Through PPARγ-Driven Cholesterol Efflux Restoration and Disruption of Lipid Raft-Organized TLR9/MyD88 Signaling Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Miao Zhang,Xinyu Pan,Yuanfang He,Kairong Sun,Zhiyu Wang,Weiyu Tian,Haonan Qiu,Yiqi Wang,Chengping Wen,Juan Chen

Journal of translational medicine 23:845 PubMed40722170

2025

Chronic intermittent hypoxia impairs BM-MSC osteogenesis and long bone growth through regulating histone lactylation.

Applications

Unspecified application

Species

Unspecified reactive species

Fang Chen,Meizhen Gu,Hongming Xu,Shasha Zhou,Zilu Shen,Xiaoyan Li,Liangchao Dong,Pin Li

Molecular medicine (Cambridge, Mass.) 31:243 PubMed40537740

2025

Dehydrocostus lactone attenuates atherogenesis by promoting cholesterol efflux and inhibiting inflammation via TLR2/PPAR-γ/NF-κB signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Weitao Hong,Xiaojia Chen,Jiahai Xiao,Gengji Chen,Jiali Yang,Pengfei Zhang,Zhizhen Zhang

Metabolites 15: PubMed40422873

2025

Compound 3d Attenuates Metabolic Dysfunction-Associated Steatohepatitis via Peroxisome Proliferator-Activated Receptor Pathway Activation and Inhibition of Inflammatory and Apoptotic Signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Shouqing Zhang,Jiajia Yu,Sule Bai,Shuhan Li,Quanyuan Qiu,Xiangshun Kong,Cen Xiang,Zhen Liu,Peng Yu,Yuou Teng

Frontiers in pharmacology 16:1569888 PubMed40308754

2025

The antidepressant effects of kaji-ichigoside F1 via activating PPAR-γ/CX3CR1/Nrf2 signaling and suppressing NF-κB/NLRP3 signaling pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Maoyang Huang,Faju Chen,Lang Zhou,Qing Zhang,Li Wang,Liangqun Li,Lishou Yang,Ming Gao,Lilang Li,Yu Wang,Juan Yang,Guanping Yao,Qiji Li,Xiaosheng Yang

Clinical, cosmetic and investigational dermatology 18:989-998 PubMed40296866

2025

Myosin 1b Inhibits the Phenotype of HemECs to Affect the Progression of Infantile Hemangiomas.

Applications

Unspecified application

Species

Unspecified reactive species

Nanxi Li,Xiangan Gong,Zhongying Cao,Zhiyu Li,Luying Wang,Ran Huo,Cong Fu

Allergologia et immunopathologia 53:52-58 PubMed40088022

2025

Echinocystic acid activates PPARγ to alleviate mannan-induced psoriasis and psoriatic arthritis in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Chengwei Yu,Huiming Wu,Dongrui Zhao,Huajie Shi

Journal of cellular and molecular medicine 29:e70456 PubMed40008494

2025

Pioglitazone Regulates Chondrocyte Metabolism and Attenuates Osteoarthritis by Activating Peroxisome Proliferator-Activated Receptor Gamma.

Applications

Unspecified application

Species

Unspecified reactive species

Jiaqi Shi,Tianlun Gong,Yi Zhou

Nature communications 15:10889 PubMed39738070

2024

ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B.

Applications

Unspecified application

Species

Unspecified reactive species

Yusang Xie,Hong Mei,Wei Wang,Xiao Li,Pengfei Hu,Xingui Tian,Rong Zhou,Jia Liu,Jieming Qu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PPAR gamma antibody [EPR23297-111]

Immunocytochemistry/ Immunofluorescence - Anti-PPAR gamma antibody [EPR23297-111] (AB272718)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (50)

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Product promise