Anti-PRAM1 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

PRAM1 influences immune cell function by modulating intracellular signaling pathways. It does not work alone as it is part of larger signaling complexes interacting with other proteins to transmit extracellular signals into cellular responses. Through its adaptor role PRAM1 influences cellular processes like differentiation proliferation and apoptosis specifically in immune cells. This involvement highlights its importance in maintaining immune system balance and response to external stimuli.

Pathways

The PRAM1 protein participates in key signaling networks like the MAPK and NF-kB pathways. In these pathways PRAM1 interacts with proteins such as SOS and MEKK1 representing important nodes in the cascade. The MAPK pathway plays a significant role in cellular responses to stress and mitogenic signals while the NF-kB pathway is central to immune response regulation and inflammatory processes. PRAM1's participation in these critical pathways reflects its broader impact on cellular signaling and function.