Anti-Prostaglandin E Receptor EP1/PTGER1 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

PTGER1 plays a significant role in modulating vascular smooth muscle function. It does not operate as a part of a larger protein complex but rather works independently to initiate cellular responses upon binding with PGE2. The activation of PTGER1 influences various physiological processes such as inflammation pain perception and smooth muscle contraction. It achieves this by enabling the intracellular signaling that contributes to these bodily responses.

Pathways

PTGER1 functions in essential signaling cascades particularly the prostaglandin signaling pathway. Also it interfaces with the G-protein coupled receptor signaling pathway which involves proteins such as Gq/11. PTGER1 activation can both amplify and regulate the downstream signaling events linking the receptor to processes involved in inflammation and pain response.