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AB60206

Anti-Protein A antibody

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(2 Publications)

Rabbit Polyclonal Protein A antibody. Suitable for WB and reacts with Recombinant full length protein samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Staphylococcus aureus subsp. aureus NCTC 8325 spa.

View Alternative Names

SAOUHSC_00069, spa, Immunoglobulin G-binding protein A, IgG-binding protein A, Staphylococcal protein A, SpA

1 Images
Western blot - Anti-Protein A antibody (AB60206)
  • WB

Supplier Data

Western blot - Anti-Protein A antibody (AB60206)

All lanes:

Western blot - Anti-Protein A antibody (ab60206)

All lanes:

Recombinant Protein A at 0.01 µg

Predicted band size: 56 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Staphylococcus aureus

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Staphylococcus aureus subsp. aureus NCTC 8325 spa.

P02976

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Recombinant full length protein": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "0.5-4 µg/mL", "WB-species-notes": "<p></p>" }, "Staphylococcus aureus": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Product details

This product is manufactured by BioVision, an Abcam company and was previously called 5500 Protein A Antibody. 5500-100 is the same size as the 100 µg size of ab60206.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 30% Glycerol (glycerin, glycerine), 0.5% BSA
Shipped at conditions
Blue Ice
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins (PubMed : 10805799, PubMed : 2938951, PubMed : 4163007). In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin. Acts directly as a pro-inflammatory factor in the lung through its ability to bind and activate tumor necrosis factor alpha receptor 1/TNFRSF1A (By similarity).
See full target information spa
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:9619 PubMed39511195

2024

Altered genomic methylation promotes Staphylococcus aureus persistence in hospital environment.

Applications

Unspecified application

Species

Unspecified reactive species

Yuriko Yamazaki,Tomoka Ito,Seitaro Nakagawa,Takashi Sugihira,Chinami Kurita-Tachibana,Amer E Villaruz,Kensuke Ishiguro,Barbora Salcman,Shuo Li,Sanami Takada,Naohiro Inohara,Yoko Kusuya,Aki Shibata,Masakazu Tamai,Reika Aoyama,Kanako Inoue,Shota Murata,Kazuyuki Matsushita,Akiko Miyabe,Toshibumi Taniguchi,Hidetoshi Igari,Naruhiko Ishiwada,Masateru Taniguchi,Taka-Aki Nakada,Hiroyuki Matsue,Manabu Fujimoto,Haruka Hishiki,Yoshiteru Osone,Hiromichi Hamada,Naoki Shimojo,Tsutomu Suzuki,Michael Otto,Gabriel Núñez,Hiroki Takahashi,Akiko Takaya,Yuumi Nakamura

Cellular physiology and biochemistry : internation 45:832-843 PubMed29414810

2018

Knockdown of Long Non-Coding RNA RP11-445H22.4 Alleviates LPS-Induced Injuries by Regulation of MiR-301a in Osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Taitao Sun,Jian Yu,Liang Han,Shuo Tian,Bin Xu,Xianbin Gong,Qiang Zhao,Yang Wang
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
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