Anti-Protocadherin 21 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Protocadherin 21 contributes to the organization and connection of photoreceptors and is an integral component of the photoreceptor sensory cilium complex. This protein plays a role in the development and maintenance of the outer segment discs in photoreceptors which are essential for capturing light and initiating phototransduction. The organization and stability provided by PCDH21 assist in the photoreceptors' effective response to light stimulation emphasizing its importance in normal visual function.

Pathways

Photoreceptor cells rely heavily on the phototransduction cascade to convert light signals into neural signals a process in which Protocadherin 21 plays a supportive role. PCDH21 interacts with other retinal proteins such as rhodopsin which is important for the initiation of this cascade. Additionally links to the Wnt signaling pathway suggest a role in cellular communication and signal transduction highlighting PCDH21's broader interaction within cellular pathways important for proper retinal function.