Anti-Protocadherin Gamma (pan) antibody [N159/5] - C-terminal

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

Clustered gene expression in the brain results in Protocadherin Gamma being necessary for cell-cell adhesion and signaling mechanisms. The protein organizes into tetramers that form large complexes essential for synaptic specificity. Protocadherin Gamma's interactions occur at the cellular membrane involving extracellular domains that mediate contact with neighboring cells. The protein cooperates with other members of the cadherin family reinforcing cellular adhesion and structural integrity in neural tissues.

Pathways

Functional interactions in neural development prominently involve Protocadherin Gamma. This protein is integrated into the neural circuit assembly and synaptic connection pathways ensuring proper communication within the brain. Protocadherin Gamma demonstrates links to signaling proteins like neural cell adhesion molecules which assist in transmitting extracellular signals to intracellular domains. These pathways play a role in regulating synaptic plasticity which is important for learning and memory processes.