AB106834

Anti-PRX-1 antibody

Name: Anti-PRX-1 antibody (ab106834) | Abcam
Brand: Abcam Limited
SKU: AB106834
Price: 470 USD
Availability: InStock
Rating: 3 (2 reviews)

(2 Reviews)

(3 Publications)

Goat Polyclonal PRX-1 antibody. Suitable for WB and reacts with Human, Mouse samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human PRRX1 aa 50-100.

View Alternative Names

PMX1, PRRX1, Paired mesoderm homeobox protein 1, Homeobox protein PHOX1, Paired-related homeobox protein 1, PRX-1

2 Images

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Western blot - Anti-PRX-1 antibody (AB106834)

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Western blot - Anti-PRX-1 antibody (ab106834) at 2 µg/mL

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LNCaP cell lysate (35µg protein in RIPA buffer)

Predicted band size: 27 kDa

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Western blot - Anti-PRX-1 antibody (AB106834)

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Western blot - Anti-PRX-1 antibody (ab106834) at 1 µg/mL

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Mouse Heart ysate

Predicted band size: 27 kDa

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Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Human

Applications

applications

Immunogen

Synthetic Peptide within Human PRRX1 aa 50-100. The exact immunogen used to generate this antibody is proprietary information.

P54821

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.3-1 µg/mL", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.3-1 µg/mL", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Storage buffer

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Master transcription factor of stromal fibroblasts for myofibroblastic lineage progression. Orchestrates the functional drift of fibroblasts into myofibroblastic phenotype via TGF-beta signaling by remodeling a super-enhancer landscape. Through this function, plays an essential role in wound healing process (PubMed : 35589735). Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer (By similarity). May play a role in homeostasis and regeneration of bone, white adipose tissue and derm (By similarity).. Isoform 1. Transcriptional activator, when transfected in fibroblastic or myoblastic cell lines. This activity may be masked by the C-terminal OAR domain.. Isoform 2. Transcriptional repressor, when transfected in fibroblastic or myoblastic cell lines.

See full target information PRRX1

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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Translational andrology and urology 11:1116-1129 PubMed36092834

2022

PRRX1/FOXM1 reduces gemcitabin-induced cytotoxicity by regulating autophagy in bladder cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Xixi Huang,Weiping Huang,Keming Wu,Qi Lin,Gang Chen

Antioxidants (Basel, Switzerland) 11: PubMed35453370

2022

Enzymatic Depletion of Mitochondrial Inorganic Polyphosphate (polyP) Increases the Generation of Reactive Oxygen Species (ROS) and the Activity of the Pentose Phosphate Pathway (PPP) in Mammalian Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Vedangi Hambardikar,Mariona Guitart-Mampel,Ernest R Scoma,Pedro Urquiza,Gowda G A Nagana,Daniel Raftery,John A Collins,Maria E Solesio

Experimental and therapeutic medicine 18:1752-1760 PubMed31410134

2019

Effect of heme oxygenase 1 and renin/prorenin receptor on oxidized low-density lipoprotein-induced human umbilical vein endothelial cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xin Gong,Congyang Liu,Hongling Wang,Jinying Fan,Cuihong Jiang,Yong Zou

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PRX-1 antibody

Western blot - Anti-PRX-1 antibody (AB106834)

Western blot - Anti-PRX-1 antibody (AB106834)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (3)

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