AB2930

Anti-PSD93 antibody

Name: Anti-PSD93 antibody (ab2930) | Abcam
Brand: Abcam Limited
SKU: AB2930
Price: 565 USD
Availability: InStock

Be the first to review this product! Submit a review

(7 Publications)

Rabbit Polyclonal PSD93 antibody. Suitable for IHC-Fr, WB, ICC/IF and reacts with Rat, Mouse, Human samples. Cited in 7 publications. Immunogen corresponding to Synthetic Peptide within Rat Dlg2 aa 350 to C-terminus.

View Alternative Names

Dlgh2, Dlg2, Disks large homolog 2, Channel-associated protein of synapse-110, Postsynaptic density protein PSD-93, Chapsyn-110

2 Images

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

ICC/IF image of ab2930 stained PC12 cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab2930, 1µg/ml) overnight at +4°C. The secondary antibody (green) was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) used at a 1/1000 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

IHC-Fr

Supplier Data

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

Immunolocalization of PSD-93 in rat cerebellum using ab2930.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

WB, ICC/IF, IHC-Fr

applications

Immunogen

Synthetic Peptide within Rat Dlg2 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q63622

Specificity

Detects Post Synaptic Density 93 (PSD 93) from rat tissues. This antibody does not detect other synapse-associated protein family members.

style

left-column

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "3 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "3 µg/mL", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCFr-species-checked": "testedAndGuaranteed", "IHCFr-species-dilution-info": "5 µg/mL", "IHCFr-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1 µg/mL", "ICCIF-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

Preservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).

See full target information Dlg2

style

left-column

Publications (7)

Recent publications for all applications. Explore the full list and refine your search

Cells 12: PubMed36980245

2023

JNK Activation Correlates with Cognitive Impairment and Alteration of the Post-Synaptic Element in the 5xFAD AD Mouse Model.

Applications

Unspecified application

Species

Unspecified reactive species

Erica Cecilia Priori,Clara Alice Musi,Arianna Giani,Luca Colnaghi,Ivana Milic,Andrew Devitt,Tiziana Borsello,Mariaelena Repici

BMC biology 19:256 PubMed34911542

2021

JNK signaling provides a novel therapeutic target for Rett syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Clara Alice Musi,Anna Maria Castaldo,Anna Elisa Valsecchi,Sara Cimini,Noemi Morello,Riccardo Pizzo,Alessandra Renieri,Ilaria Meloni,Maurizio Bonati,Maurizio Giustetto,Tiziana Borsello

Cancer biology & therapy 20:897-911 PubMed30862230

2019

MicroRNA-23a depletion promotes apoptosis of ovarian cancer stem cell and inhibits cell migration by targeting DLG2.

Applications

Unspecified application

Species

Unspecified reactive species

Ru-Jin Zhuang,Xiao-Xu Bai,Wei Liu

Journal of Alzheimer's disease : JAD 63:1141-1159 PubMed29710724

2018

Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer's Disease-Like Pathology and Cognitive Impairments.

Applications

Unspecified application

Species

Unspecified reactive species

Yacoubou Abdoul Razak Mahaman,Fang Huang,Mengjuan Wu,Yuman Wang,Zhen Wei,Jian Bao,Maibouge Tanko Mahamane Salissou,Dan Ke,Qun Wang,Rong Liu,Jian-Zhi Wang,Bin Zhang,Dan Chen,Xiaochuan Wang

Cell death & disease 4:e673 PubMed23764854

2013

Glycation exacerbates the neuronal toxicity of β-amyloid.

Applications

Unspecified application

Species

Mouse

X-H Li,L-L Du,X-S Cheng,X Jiang,Y Zhang,B-L Lv,R Liu,J-Z Wang,X-W Zhou

The Journal of neuroscience : the official journal of the Society for Neuroscience 31:6800-8 PubMed21543610

2011

PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down.

Applications

ICC/IF

Species

Rat

Qian Sun,Gina G Turrigiano

Journal of Cancer 1:14-22 PubMed20842219

2010

Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26.

Applications

Species

Human

Ziad J Sahab,Michael D Hall,Lihua Zhang,Amrita K Cheema,Stephen W Byers

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-PSD93 antibody

Immunocytochemistry/ Immunofluorescence - Anti-PSD93 antibody (AB2930)

Immunohistochemistry (Frozen sections) - Anti-PSD93 antibody (AB2930)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

Alternative Products

Primary Antibodies

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (7)

Product promise