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Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723) is a mouse monoclonal antibody that is used to detect PSD95 in Western Blot, IHC-P. Suitable for Mouse, Rat samples.



- Over 190 publications

- Trusted since 2003


Images

Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (AB2723), expandable thumbnail
  • Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (AB2723), expandable thumbnail

Publications

Key facts

Isotype
IgG2a
Host species
Mouse
Storage buffer

pH: 7.4
Preservative: 0.02% Sodium azide
Constituents: PBS, 6.97% L-Arginine

Form
Liquid
Clonality
Monoclonal

Immunogen

  • The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IHC-PWB
Mouse
Expected
Tested
Rat
Tested
Tested
Cow
Predicted
Predicted
Zebrafish
Predicted
Predicted

Tested
Tested

Species
Rat
Dilution info
1-2 µg/mL
Notes

We do not guarantee IHC-P for mouse.

Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.

Expected
Expected

Species
Mouse
Dilution info
Use at an assay dependent concentration.
Notes

-

Predicted
Predicted

Species
Cow, Zebrafish
Dilution info
-
Notes

-

Tested
Tested

Species
Mouse
Dilution info
1-5 µg/mL
Notes

-

Species
Rat
Dilution info
1-5 µg/mL
Notes

-

Predicted
Predicted

Species
Cow, Zebrafish
Dilution info
-
Notes

-

Associated Products

Select an associated product type

4 products for Alternative Product

1 product for Alternative Version

Target data

Function

Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins (PubMed:15358775, PubMed:9853749). Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (Probable). Under basal conditions, cooperates with FYN to stabilize palmitoyltransferase ZDHHC5 at the synaptic membrane through FYN-mediated phosphorylation of ZDHHC5 and its subsequent inhibition of association with endocytic proteins (By similarity).

Alternative names

Recommended products

Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723) is a mouse monoclonal antibody that is used to detect PSD95 in Western Blot, IHC-P. Suitable for Mouse, Rat samples.



- Over 190 publications

- Trusted since 2003

Key facts

Isotype
IgG2a
Form
Liquid
Clonality
Monoclonal
Immunogen
  • The exact immunogen used to generate this antibody is proprietary information.
Clone number
6G6-1C9
Purification technique
Affinity purification
Specificity

We do not guarantee IHC-P for mouse.

Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

What is this antibody validated in?


Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Mouse, Rat samples.

What is the molecular weight of PSD95?


Anti-PSD95 [6G6-1C9] - Synaptic Marker (ab2723) specifically detects a band for PSD95 (UniProt: P31016) at a molecular weight of 80kDa.

Trusted by the scientific community


Anti-PSD95 [6G6-1C9] - Synaptic Marker (ab2723) was first used in a scientific publication in 2003 and has been cited over 190 times in peer-reviewed journals.

Reviewed by scientists


Anti-PSD95 [6G6-1C9] - Synaptic Marker (ab2723) has over 10 independent reviews from customers.

Other related products


We have a range of other formats of antibody clone [6G6-1C9] also available for your convenience:
ab2723, Carrier free - Anti-PSD95 antibody [6G6-1C9] - BSA and Azide free ab264091



Want a custom formulation?
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723), expandable thumbnail

    Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723)

    All lanes: Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723) at 5 µg/mL

    Lane 1: Hippocampus (Rat) Tissue Lysate at 20 µg

    Lane 2: Forebrain (Rat) Tissue Lysate at 20 µg

    Lane 3: Hippocampus (Mouse) Tissue Lysate at 20 µg

    Lane 4: Forebrain (Mouse) Tissue Lysate at 20 µg

    Secondary

    All lanes: Western blot - Goat Anti-Mouse IgG H&L (HRP) preadsorbed (Goat Anti-Mouse IgG H&L (HRP) preadsorbed ab97040) at 1/5000 dilution

    Performed under reducing conditions.

    Predicted band size: 80 kDa

    Observed band size: 100 kDa, 110 kDa, 80 kDa, 95 kDa

    Exposure time: 3min

  • Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723), expandable thumbnail
    Image courtesy of a customer review submitted by Grant Corbett

    Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723)

    All lanes: Western blot - Anti-PSD95 antibody [6G6-1C9] - Synaptic Marker (ab2723) at 1/1200 dilution

    Lanes 1 - 6: Mouse Hippocampus at 30 µg with Li-Cor Block Buffer, 1 hour at 21°C

    Lanes 7 - 12: Mouse Liver at 30 µg with Li-Cor Block Buffer, 1 hour at 21°C

    Secondary

    All lanes: Li-Cor IRDye® Donkey anti-mouse 680LT at 1/18000 dilution

    Performed under reducing conditions.

    Predicted band size: 80 kDa

    Observed band size: 95 kDa

    Exposure time: 5min

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com