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AB172628

Anti-PSD95 (phospho T19) antibody [EPR2619(2)]

5

(1 Review)

|

(5 Publications)

Rabbit Recombinant Monoclonal PSD95 phospho T19 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.

View Alternative Names

PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, PSD-95, SAP-90, SAP90

1 Images
Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628)
  • WB

Supplier Data

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628)

All lanes:

Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (ab172628) at 1/1000 dilution

Lane 1:

Fetal brain lysate, untreated at 10 µg

Lane 2:

Fetal brain lysate, treated with Lambda Phosphatase at 10 µg

Predicted band size: 80 kDa

false

  • Carrier free

    Anti-PSD95 (phospho T19) antibody [EPR2619(2)] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR2619(2)

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" }, "Mouse": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (By similarity). Under basal conditions, cooperates with FYN to stabilize palmitoyltransferase ZDHHC5 at the synaptic membrane through FYN-mediated phosphorylation of ZDHHC5 and its subsequent inhibition of association with endocytic proteins (PubMed : 26334723).
See full target information DLG4 phospho T19
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Brain research bulletin 165:272-280 PubMed33075417

2020

Effects of chronic ethanol consumption on the expression of GLT-1 and neuroplasticity-related proteins in the nucleus accumbens of alcohol-preferring rats.

Applications

Unspecified application

Species

Unspecified reactive species

Hasan Alhaddad,Fawaz Alasmari,Balsam Alhamadani,Woonyen Wong,Richard L Bell,Youssef Sari

Frontiers in cellular neuroscience 13:447 PubMed31749684

2019

Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Mice Contributes to Synaptic and Social Deficiency.

Applications

Unspecified application

Species

Unspecified reactive species

Mengmeng Wang,Xinyan Liu,Yilin Hou,Haifeng Zhang,Junjun Kang,Fei Wang,Youyi Zhao,Jing Chen,Xufeng Liu,Yazhou Wang,Shengxi Wu

The EMBO journal 37:122-138 PubMed29118000

2017

Ca/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down.

Applications

Unspecified application

Species

Unspecified reactive species

Dhrubajyoti Chowdhury,Matthew Turner,Tommaso Patriarchi,Anne C Hergarden,David Anderson,Yonghong Zhang,Junqing Sun,Chao-Yin Chen,James B Ames,Johannes W Hell

Frontiers in molecular neuroscience 10:295 PubMed28979184

2017

SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus.

Applications

Unspecified application

Species

Unspecified reactive species

Dae Hwan Kim,Minkyung Kang,Chong-Hyun Kim,Yun Hyun Huh,In Ha Cho,Hyun-Hee Ryu,Kyung Hwun Chung,Chul-Seung Park,Sangmyung Rhee,Yong-Seok Lee,Woo Keun Song

Bipolar disorders 18:473-480 PubMed27687706

2016

Ketamine-induced inhibition of glycogen synthase kinase-3 contributes to the augmentation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Eléonore Beurel,Steven F Grieco,Celeste Amadei,Kimberlee Downey,Richard S Jope
View all publications
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Product promise

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