Rabbit Recombinant Monoclonal PSD95 phospho T19 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.
Images
![Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628), expandable thumbnail](https://content.abcam.com/products/images/psd95-phospho-t19-antibody-epr26192-ab172628--western-blot-img105622.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (AB172628)")
Publications
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- Brain research bulletin 165:272-2802020Effects of chronic ethanol consumption on the expression of GLT-1 and neuroplasticity-related proteins in the nucleus accumbens of alcohol-preferring rats.Applications:Unspecified applicationReactive species:Unspecified reactive speciesHasan Alhaddad,Fawaz Alasmari,Balsam Alhamadani,Woonyen Wong,Richard L Bell,Youssef SariPubMed 33075417
- Frontiers in cellular neuroscience 13:4472019Decrease of GSK-3β Activity in the Anterior Cingulate Cortex of Mice Contributes to Synaptic and Social Deficiency.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMengmeng Wang et. al.PubMed 31749684
- The EMBO journal 37:122-1382017Ca/calmodulin binding to PSD-95 mediates homeostatic synaptic scaling down.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDhrubajyoti Chowdhury,Matthew Turner,Tommaso Patriarchi,Anne C Hergarden,David Anderson,Yonghong Zhang,Junqing Sun,Chao-Yin Chen,James B Ames,Johannes W HellPubMed 29118000
- Frontiers in molecular neuroscience 10:2952017SPIN90 Modulates Long-Term Depression and Behavioral Flexibility in the Hippocampus.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDae Hwan Kim et. al.PubMed 28979184
- Bipolar disorders 18:473-4802016Ketamine-induced inhibition of glycogen synthase kinase-3 contributes to the augmentation of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor signaling.Applications:Unspecified applicationReactive species:Unspecified reactive speciesEléonore Beurel,Steven F Grieco,Celeste Amadei,Kimberlee Downey,Richard S JopePubMed 27687706
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9% PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
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Reactivity data
Select an application| ICC/IF | WB | IHC-P | |
|---|---|---|---|
| Human | Not recommended | Tested | Not recommended |
| Mouse | Not recommended | Predicted | Not recommended |
| Rat | Not recommended | Predicted | Not recommended |
ICC/IF
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 - 1/10000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Rat | Dilution info - | Notes - |
IHC-P
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Human, Mouse, Rat | Dilution info - | Notes - |
Associated Products
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Target data
Function
Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression (By similarity). Under basal conditions, cooperates with FYN to stabilize palmitoyltransferase ZDHHC5 at the synaptic membrane through FYN-mediated phosphorylation of ZDHHC5 and its subsequent inhibition of association with endocytic proteins (PubMed:26334723).
Alternative names
PSD95, DLG4, Disks large homolog 4, Postsynaptic density protein 95, Synapse-associated protein 90, PSD-95, SAP-90, SAP90
Recommended products
Rabbit Recombinant Monoclonal PSD95 phospho T19 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 9% PBS, 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR2619(2)
- Purity
- Tissue culture supernatant
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
![Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (ab172628), expandable thumbnail](https://content.abcam.com/products/images/psd95-phospho-t19-antibody-epr26192-ab172628--western-blot-img105622.jpg "Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (ab172628)")
Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (ab172628)
All lanes: Western blot - Anti-PSD95 (phospho T19) antibody [EPR2619(2)] (ab172628) at 1/1000 dilution
Lane 1: Fetal brain lysate, untreated at 10 µg
Lane 2: Fetal brain lysate, treated with Lambda Phosphatase at 10 µg
Predicted band size: 80 kDa
Downloads
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