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AB69232

Anti-Pseudomonas aeruginosa serotype 5c antibody [SD6930]

5

(1 Review)

|

(3 Publications )

Mouse Monoclonal Pseudomonas aeruginosa serotype 5c antibody. Suitable for ELISA, ICC/IF and reacts with Pseudomonas aeruginosa samples. Cited in 3 publications. Immunogen corresponding to Cell preparation containing Pseudomonas aeruginosa serotype 5c protein.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

SD6930

Isotype

IgG1

Carrier free

No

Reacts with

Pseudomonas aeruginosa

Applications

ELISA, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Primary Antibodies

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Anti-E. coli antibody

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Pseudomonas aeruginosa": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
Preservative: 0.065% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Pseudomonas aeruginosa serotype 5c is a lipopolysaccharide antigen found on the outer membrane of the Pseudomonas aeruginosa bacterium. This serotype is associated with the specific O-antigen portion of the bacterial lipopolysaccharide but does not have an alternate name. The molecular mass for this lipopolysaccharide varies due to its complex structure. Pseudomonas aeruginosa serotype 5c is expressed on the cell surface where it plays a significant role in bacterial immune evasion and survival in hostile environments.
Biological function summary

This serotype contributes to the bacterium's ability to resist phagocytosis and avoid detection by the host’s immune system. It is not part of a multiprotein complex but interacts directly with components of the host immune system. The structure of the lipopolysaccharide helps in maintaining bacterial structural integrity and can trigger inflammatory responses from the host.

Pathways

Pseudomonas aeruginosa serotype 5c engages in pathways involving bacterial defense mechanisms and host-pathogen interactions. It plays a part in the lipopolysaccharide biosynthesis pathway which involves several enzymes responsible for the assembly of this complex molecule. It also participates in signaling pathways that modulate the host immune response indirectly interacting with immune-related proteins such as TLR4 which is a receptor in innate immunity pathways.

Pseudomonas aeruginosa serotype 5c is strongly linked to respiratory infections like pneumonia especially in immunocompromised individuals. This serotype significantly contributes to the virulence and persistence of the bacteria in diseases like cystic fibrosis due to its resistance to host defense mechanisms. Chronic colonization in the respiratory tract often involves interactions with host proteins including CFTR a protein affecting mucus clearance in cystic fibrosis compounding the disease's severity.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Pseudomonas aeruginosa serotype 5c

Alternative Names

P. aeruginosa, Pseudomonas aeruginosa
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 11:1242 PubMed32144270

2020

CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Joon-Il Jun,Lester F Lau

Scientific reports 7:14683 PubMed29089624

2017

Combating virulence of Gram-negative bacilli by OmpA inhibition.

Applications

ICC/IF

Species

Unspecified reactive species

Xavier Vila-Farrés,Raquel Parra-Millán,Viviana Sánchez-Encinales,Monica Varese,Rafael Ayerbe-Algaba,Nuria Bayó,Salvador Guardiola,María Eugenia Pachón-Ibáñez,Martin Kotev,Jesús García,Meritxell Teixidó,Jordi Vila,Jerónimo Pachón,Ernest Giralt,Younes Smani

Antimicrobial agents and chemotherapy 58:4264-74 PubMed24820078

2014

Epinecidin-1 has immunomodulatory effects, facilitating its therapeutic use in a mouse model of Pseudomonas aeruginosa sepsis.

Applications

Unspecified application

Species

Unspecified reactive species

Chieh-Yu Pan,Jian-Chyi Chen,Jenn-Feng Sheen,Tai-Lang Lin,Jyh-Yih Chen
View all publications
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Product promise

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