AB58779

Anti-PSMA antibody

Name: Anti-PSMA antibody (ab58779) | Abcam
Brand: Abcam Limited
SKU: AB58779
Price: 620 USD
Availability: InStock

Be the first to review this product! Submit a review

(4 Publications)

Rabbit Polyclonal PSMA antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications.

View Alternative Names

FOLH, NAALAD1, PSM, PSMA, GIG27, FOLH1, Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated-alpha-linked acidic dipeptidase I, Prostate-specific membrane antigen, Pteroylpoly-gamma-glutamate carboxypeptidase, FGCP, GCPII, mGCP, NAALADase I

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PSMA antibody (AB58779)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PSMA antibody (AB58779)

Human prostate carcinoma stained with ab58779 at a dilution of 1/100

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.6 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

See full target information FOLH1

style

left-column

Publications (4)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 24: PubMed37511087

2023

Synthesis of Prostate-Specific Membrane Antigen-Targeted Bimodal Conjugates of Cytotoxic Agents and Antiandrogens and Their Comparative Assessment with Monoconjugates.

Applications

Unspecified application

Species

Unspecified reactive species

Nikolai Y Zyk,Anastasiia S Garanina,Ekaterina A Plotnikova,Anton P Ber,Ekaterina A Nimenko,Natalia S Dashkova,Anastasiia A Uspenskaia,Radik R Shafikov,Dmitry A Skvortsov,Stanislav A Petrov,Andrey A Pankratov,Nikolai V Zyk,Alexander G Majouga,Elena K Beloglazkina,Aleksei E Machulkin

Molecular imaging 2022:5358545 PubMed35517711

2022

Prostate-Specific Membrane Antigen as Target for Neuroimaging of Central Nervous System Tumors.

Applications

Unspecified application

Species

Unspecified reactive species

Brittany M Stopa,James Crowley,Csaba Juhász,Cara M Rogers,Mark R Witcher,Jackson W Kiser

EJNMMI research 10:55 PubMed32451793

2020

High uptake of Ga-PSMA and F-DCFPyL in the peritumoral area of rat gliomas due to activated astrocytes.

Applications

Unspecified application

Species

Unspecified reactive species

Dennis Oliveira,Carina Stegmayr,Alexander Heinzel,Johannes Ermert,Bernd Neumaier,N Jon Shah,Felix M Mottaghy,Karl-Josef Langen,Antje Willuweit

Nature communications 8:15870 PubMed28627514

2017

Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC.

Applications

Unspecified application

Species

Unspecified reactive species

Junchao Cai,Lishan Fang,Yongbo Huang,Rong Li,Xiaonan Xu,Zhihuang Hu,Le Zhang,Yi Yang,Xun Zhu,Heng Zhang,Jueheng Wu,Yan Huang,Jun Li,Musheng Zeng,Erwei Song,Yukai He,Li Zhang,Mengfeng Li

View all publications

style

left-column

style

left-column

style

right-column

Alternative Products

Primary Antibodies

AB201253

Biotin Anti-PSMA antibody [EPR6253]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Biotin Anti-PSMA antibody [EPR6253] (AB201253)

Primary Antibodies

AB133579

Anti-PSMA antibody [EPR6253]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PSMA antibody [EPR6253] (AB133579)

Primary Antibodies

AB76104

Anti-PSMA antibody [EP3253]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-PSMA antibody [EP3253] (AB76104)

Primary Antibodies

AB79542

Anti-PSMA antibody [EP3254]

RabMAb|Recombinant

Western blot - Anti-PSMA antibody [EP3254] (AB79542)

Primary Antibodies

AB64082

Anti-PSMA antibody [SP29]

RabMAb|Recombinant|20ul selling size

Primary Antibodies

AB245747

Anti-PSMA antibody [SP29] - BSA and Azide free

RabMAb|Recombinant

Primary Antibodies

AB226141

Anti-PSMA antibody [EPR6253] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PSMA antibody [EPR6253] - BSA and Azide free (AB226141)

Complementary Products

Assay Kits

AB315305

Human PSMA ELISA Kit

SimpleStep

Sandwich ELISA - Human PSMA ELISA Kit (AB315305)

Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

Immunocytochemistry/ Immunofluorescence - Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (AB150077)

Primary Antibodies

AB76113

Anti-Prostate Specific Antigen antibody [EP1588Y]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Prostate Specific Antigen antibody [EP1588Y] (AB76113)

Primary Antibodies

AB28364

Anti-CD31 antibody

BOND RX™ Validated|Lab Essentials

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD31 antibody (AB28364)

Primary Antibodies

AB71916

Anti-EpCAM antibody

BOND RX™ Validated

Immunocytochemistry/ Immunofluorescence - Anti-EpCAM antibody (AB71916)

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com