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AB66912

Anti-PSMA antibody [GCP-05]

1

(1 Review)

|

(9 Publications)

Mouse Monoclonal PSMA antibody. Suitable for Flow Cyt and reacts with Human samples. Cited in 9 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FOLH1 aa 1-750.

View Alternative Names

FOLH, NAALAD1, PSM, PSMA, GIG27, FOLH1, Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated-alpha-linked acidic dipeptidase I, Prostate-specific membrane antigen, Pteroylpoly-gamma-glutamate carboxypeptidase, FGCP, GCPII, mGCP, NAALADase I

2 Images
Flow Cytometry - Anti-PSMA antibody [GCP-05] (AB66912)
  • Flow Cyt

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Flow Cytometry - Anti-PSMA antibody [GCP-05] (AB66912)

This image shows LNCaP cell line stained by ab66911 and ab66912. Green column - antibodies at 1μg/ml; Blue column - antibodies at 5μg/ml; Yellow column - negative cell line.

Flow Cytometry - Anti-PSMA antibody [GCP-05] (AB66912)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-PSMA antibody [GCP-05] (AB66912)

Flow cytometry analysis of PSMA positive LNCaP cells stained with ab66912 (green) and PSMA negative HeLa cells (blue)

  • 578 PE

    PE Anti-PSMA antibody [GCP-05]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

GCP-05

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Fragment Protein within Human FOLH1 aa 1-750. The exact immunogen used to generate this antibody is proprietary information.

Q04609

Epitope

This antibody recognizes the extracellular domain of PSMA.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-4 µg/mL", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }
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Product details

This product was changed from ascites to tissue culture supernatant on 24th January 2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Purification notes
Purity: > 95%Purified from TCS
Storage buffer
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression.. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
See full target information FOLH1
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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

International journal of nanomedicine 19:4995-5010 PubMed38832336

2024

Multimodal, PSMA-Targeted, PAMAM Dendrimer-Drug Conjugates for Treatment of Prostate Cancer: Preclinical Evaluation.

Applications

Unspecified application

Species

Unspecified reactive species

Wojciech G Lesniak,Srikanth Boinapally,Gabriela Lofland,Zirui Jiang,Catherine A Foss,Babak Behman Azad,Anna Jablonska,Mauro A Garcia,Maria Brzezinski,Martin G Pomper

Cancers 14: PubMed35681683

2022

Use of Glycoproteins-Prostate-Specific Membrane Antigen and Galectin-3 as Primary Tumor Markers and Therapeutic Targets in the Management of Metastatic Prostate Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Satish Sharma,Katherine Cwiklinski,Donald E Sykes,Supriya D Mahajan,Kent Chevli,Stanley A Schwartz,Ravikumar Aalinkeel

Scientific reports 11:15000 PubMed34294841

2021

Diagnostic potential of serum extracellular vesicles expressing prostate-specific membrane antigen in urologic malignancies.

Applications

Unspecified application

Species

Unspecified reactive species

Kyojiro Kawakami,Yasunori Fujita,Taku Kato,Kengo Horie,Takuya Koie,Keitaro Umezawa,Hiroki Tsumoto,Yuri Miura,Yasuo Katagiri,Tatsuhiko Miyazaki,Ikuroh Ohsawa,Kosuke Mizutani,Masafumi Ito

Biointerphases 15:031002 PubMed32414237

2020

Plasma enabled devices for the selective capture and photodynamic identification of prostate cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Hanieh Safizadeh Shirazi,Kit Man Chan,Julien Rouget,Kola Ostrikov,Kym McNicholas,Jordan Li,Lisa Butler,Jonathan M Gleadle,Krasimir Vasilev,Melanie MacGregor

Scientific reports 8:8867 PubMed29891921

2018

Prostate-Specific Membrane Antigen-Targeted Site-Directed Antibody-Conjugated Apoferritin Nanovehicle Favorably Influences In Vivo Side Effects of Doxorubicin.

Applications

Unspecified application

Species

Unspecified reactive species

Simona Dostalova,Hana Polanska,Marketa Svobodova,Jan Balvan,Olga Krystofova,Yazan Haddad,Sona Krizkova,Michal Masarik,Tomas Eckschlager,Marie Stiborova,Zbynek Heger,Vojtech Adam

Biomacromolecules 18:201-209 PubMed28001364

2016

In- and IRDye800CW-Labeled PLA-PEG Nanoparticle for Imaging Prostate-Specific Membrane Antigen-Expressing Tissues.

Applications

Unspecified application

Species

Unspecified reactive species

Sangeeta R Banerjee,Catherine A Foss,Allen Horhota,Mrudula Pullambhatla,Kevin McDonnell,Stephen Zale,Martin G Pomper

The Prostate 76:215-25 PubMed26499105

2015

Characterization of a novel metastatic prostate cancer cell line of LNCaP origin.

Applications

Unspecified application

Species

Unspecified reactive species

Mark A Castanares,Ben T Copeland,Wasim H Chowdhury,Minzhi M Liu,Ronald Rodriguez,Martin G Pomper,Shawn E Lupold,Catherine A Foss

The Prostate 74:1674-90 PubMed25262926

2014

Comparative analysis of monoclonal antibodies against prostate-specific membrane antigen (PSMA).

Applications

Unspecified application

Species

Unspecified reactive species

J Tykvart,V Navrátil,F Sedlák,E Corey,M Colombatti,G Fracasso,F Koukolík,C Bařinka,P Sácha,J Konvalinka

ACS nano 6:7752-7762 PubMed22866897

2012

PSMA-targeted theranostic nanoplex for prostate cancer therapy.

Applications

Unspecified application

Species

Unspecified reactive species

Zhihang Chen,Marie-France Penet,Sridhar Nimmagadda,Cong Li,Sangeeta R Banerjee,Paul T Winnard,Dmitri Artemov,Kristine Glunde,Martin G Pomper,Zaver M Bhujwalla
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

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